Peritoneal drainage or no drainage after pancreaticoduodenectomy and/or distal pancreatectomy: a meta-analysis and syste
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and Other Interventional Techniques
Peritoneal drainage or no drainage after pancreaticoduodenectomy and/or distal pancreatectomy: a meta‑analysis and systematic review Yunxiao Lyu1 · Yunxiao Cheng1 · Bin Wang1 · Sicong Zhao1 · Liang Chen1 Received: 23 August 2019 / Accepted: 28 November 2019 © Springer Science+Business Media, LLC, part of Springer Nature 2019
Abstract Background Peritoneal drainage has been used routinely after pancreaticoduodenectomy (PD) or distal pancreatectomy (DP). Our objective was to compare patients’ outcomes after PD or DP with or without peritoneal drainage. Methods We performed a systematic search using the following databases: PubMed, Embase, Web of Science, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov until 1 June 2019. We included trials comparing no peritoneal drainage versus drainage after PD and/or DP. Results Ten trials involving 2419 patients were eligible for inclusion. The meta-analysis showed a significantly lower rate of postoperative pancreatic fistula in the no-drain group (odds ratio [OR] 0.39; 95% confidence interval [CI] 0.29–0.51; p
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