Personalized Medicine with a Nanochemistry Twist Nanomedicine

Barriers in Nanomedicine: The Importance of Defined Chemistry and Engineering Approaches for Clinical Translation --Huei-Huei Chang, Shaneen Braswell, Jonathan George, Mark Gryka, Sumin Kim, Nicolas Kolmodin, Manu Kumar, Benjamin Seadler, Oluwayemisi Sono

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Dipanjan Pan  Editor

Personalized Medicine with a Nanochemistry Twist Nanomedicine

20

Topics in Medicinal Chemistry

Editorial Board: P.R. Bernstein, Rose Valley, USA A. Buschauer, Regensburg, Germany G.I. Georg, Minneapolis, USA J.A. Lowe, Stonington, USA N.A. Meanwell, Wallingford, USA A.K. Saxena, Lucknow, India U. Stilz, Malov, Denmark C.T. Supuran, Sesto Fiorentino, Italy

Aims and Scope Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the new topic-related series Topics in Medicinal Chemistry will cover all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. In references Topics in Medicinal Chemistry is abbreviated Top Med Chem and is cited as a journal.

More information about this series at http://www.springer.com/series/7355

Dipanjan Pan Editor

Personalized Medicine with a Nanochemistry Twist Nanomedicine

With contributions by F.B. Bombelli  S. Braswell  J. Caffarini  H.-H. Chang  E.A. Daza  D. Di Silvio  D. Frankowski  J. George  D. Goatz  M. Gryka  M. Imgruet  N. Kelleher  S. Kim  N. Kolmodin  C.C. Konopka  M. Kumar  J. Kus  R. Lake  M. Mazurek  M. Modak  A. Nandyala  N. Olsen  F. Ostadhossein  D. Pan  D. Patel  A. Schwartz-Duval  B. Seadler  V. Sherwood  S. Slania  O. Sonoiki  S. Venkataraman  S. Wang  R.C. Yada  A. Zimmer

Editor Dipanjan Pan Department of Bioengineering University of Illinois at Urbana Champain Urbana, Illinois USA

ISSN 1862-2461 ISSN 1862-247X (electronic) Topics in Medicinal Chemistry ISBN 978-3-319-33544-5 ISBN 978-3-319-33546-9 (eBook) DOI 10.1007/978-3-319-33546-9 Library of Congress Control Number: 2016938785 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publis