Pharmacological Control of Calcium and Potassium Homeostasis Biologi

As the number of drugs acting on calcium and potassium channels grows, there is a need for a continuous reappraisal of the cellular machinery controlling them. The present volume provides an update on the basic knowledge, the molecular targets of the two

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Medical Science Symposia Series Volume 9

The titles published in this series are listed at the end of this volume.

Pharmacological Control of Calcium and Potassium Homeostasis Biological, Therapeutical, and Clinical Aspects Edited by

T. Godfraind Laboratory of Pharmacology, Catholic University ofLouvain, Brussels, Belgium

G. Mancia Center of Physiology, Hypertension Clinic, University of Milan, Milan, Italy

M. P. Abbracchio Institute of Pharmacological Sciences, University of Milan, Milan, Italy

L. Aguilar-Bryan Baylor College of Medicine, Houston, Texas, U.S.A.

and S. Govoni Institute of Pharmacology, University ofPavia, Pavia, Italy

SPRINGER SCIENCE+BUSINESS MEDIA, B.V.

Fondazione Giovanni Lorenzini, Milan, Italy Giovanni Lorenzini Medical Foundation, Houston, U.S.A.

Library of Congress Cataloging-in-Publication Data P h a r m a c o l o g i c a l c o n t r o l o f c a l c i u m and p o t a s s i u m h o m e o s t a s i s ; b i o l o g i c a l , t h e r a p e u t i c a l , and c l i n i c a l a s p e c t s / e d i t e d by T. G o d f r a ind ... l e t a 1 . ] . p. cm. — ( M e d i c a l s c i e n c e s y - o o s l a s e r i e s ; v. 9 ) " P r e s e n t e d a t t h e 6 t h I n t e r n a t i o n a l Symposium on P h a r m a c o l o g i c a l C o n t r o l of C a l c i u m and P o t a s s i u r a H o m e o s t a s i s : B i o l o g i c a l , T h e r a p e u t i c a l , and C l i n i c a l A s p e c t s . 1n F l o r e n c e ( I t a l y ) on O c t o b e r 4-6, 1 9 9 4 " — P r e f . I n c l u d e s Index.

ISBN 978-94-010-4056-3 ISBN 978-94-011-0117-2 (eBook) DOI 10.1007/978-94-011-0117-2 1. C a l c i u m — A n t a g o n i s t s — C o n g r e s s e s . " 2 C a i c i u m - - M e t a b o 1 i s m - E f f e c t of d r u g s o n — C o n g r e s s e s . 3. P o t a s s i u m — M e t a b o l i s m — E f f e c t of d r u g s o n - - C o n g r e s s e s . 4. P o t a s s i u m — A g o n i s t s — C o n g r e s s e s . 5. C a r d i o v a s c u l a r system—Diseases—Chemotherapy—Congresses. 6. C a l c i u m — C h a n n e l s — C o n g r e s s e s . 7. P o t a s s i u m — C h a n n e l s -Congresses. I . G o d f r a i n d , T. ( T h e o p h i l e ) I I . I n t e r n a t i o n a l Symposium on P h a r m a c o l o g i c a l C o n t r o l o f C a l c i u m and P o t a s s i u m H o m e o s t a s i s : B i o l o g i c a l , T h e r a p e u t i c a l , and C l i n i c a l A s p e c t s ( 6 t h : 1994 : F l o r e n c e , I t a l y ) I I I . Series. [DNLM: 1. C a r d i o v a s c u l a r S y s t e m — m e t a b o l i s m — c o n g r e s s e s . 2. C a r d i o v a s c u l a r D i s e a s e s — d r u g t h e r a p y — c o n g r e s s e s . 3. C a l c i u m -physlolagy—congresses. 4. C a l c l u » — a n t a g o n i s t s & m h t b i t o r s -congresses. 5. P o t a s s i u m — m e t a b o l i s m — c o n g r e s s e s . 6. P o t a s s i u m Channels—physiology—congresses. 7. H o m e o s t a s i s — c o n g r e s s e s . W1 ME46R0 v.9 1995 / WG 102 P536 19951 RC684.C34P46 1995 616. 1*06--dc20 DNLM/DLC f o r L i b r a r y of Congress 9