Physical Properties of Polymers Handbook

This handbook offers concise information on the properties of polymeric materials, particularly those most relevant to the areas of physical chemistry and chemical physics. In the second edition of Physical Properties of Polymers Handbook, each

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olymers as Biomaterials for Tissue Engineering and Controlled Drug Delivery Lakshmi S. Nair1 · Cato T. Laurencin2,3,4 (u) 1 Department

of Orthopaedic Surgery, College of Medicine, University of Virginia, Charlottesville, VA 22903, USA 2 Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA [email protected] 3 Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA 4 The University of Virginia, 400 Ray C. Hunt Drive, Suite 330, Charlottesville, VA 22903, USA 1

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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2 2.1 2.1.1 2.1.2 2.1.3 2.1.4 2.1.5 2.1.6 2.1.7 2.2 2.2.1 2.2.2 2.2.3

Biodegradable Polymers . . . . . . . Synthetic Biodegradable Polymers . Aliphatic Polyesters . . . . . . . . . Poly(ortho esters) . . . . . . . . . . Polyanhydrides . . . . . . . . . . . . Poly(alkyl cyanoacrylates) . . . . . . Poly(amino acids) . . . . . . . . . . Polyphosphazenes . . . . . . . . . . Polyphosphoesters . . . . . . . . . . Natural Biodegradable Polymers . . Polysaccharides . . . . . . . . . . . . Proteins . . . . . . . . . . . . . . . . Bacterial Polyesters and Polyamides

3 3.1 3.2 3.2.1 3.2.2 3.2.3 3.2.4 3.2.5

Biodegradable Polymers for Scope of Tissue Engineering Engineered Tissues . . . . . Skin Regeneration . . . . . Nerve Regeneration . . . . Liver . . . . . . . . . . . . . Cartilage . . . . . . . . . . Bone . . . . . . . . . . . . .

4 4.1 4.2 4.2.1

Biodegradable Polymers in Drug Delivery Scope of Controlled Drug Delivery . . . . Polymeric Drug Delivery Systems . . . . . Applications of Biodegradable Polymers .

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Tissue Engineering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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