Pre-exposure Prophylaxis (PrEP) Awareness and Prescribing Behaviors Among Primary Care Providers: DocStyles Survey, 2016

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ORIGINAL PAPER

Pre‑exposure Prophylaxis (PrEP) Awareness and Prescribing Behaviors Among Primary Care Providers: DocStyles Survey, 2016–2020, United States Jamal T. Jones1   · B. Rey deCastro2 · Euna M. August2 · Dawn K. Smith2 Accepted: 8 November 2020 © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2020

Abstract Few studies have assessed providers’ intent of prescribing PrEP in the future. We analyzed cross-sectional web-based surveys to estimate trends from 2016 to 2020 in PrEP awareness and prescribing behaviors in the United States among primary care providers. Multivariable logistic regression was used to estimate prevalence of PrEP awareness, prescribing behaviors, and likelihood of prescribing PrEP in the next 12 months. The adjusted prevalence for PrEP awareness was significantly higher in 2019 (93.7%, 95% CI 91.9%, 95.2%) compared to 2018 (88.1%, 95% CI 85.5%, 90.3%). The adjusted prevalence for prescribing PrEP was significantly higher in 2019 (16.4%, 95% CI 13.6%, 19.6%) and 2020 (15.6%, 95% CI 13.0%, 18.7%) compared to 2018 (12.2%, 95% CI 10.0%, 14.7%). Practicing in the West and regularly screening for HIV were associated with higher PrEP awareness and provision. Studies should examine factors associated with PrEP provision for groups with increased risk for HIV. Keywords  HIV prevention · Pre-exposure prophylaxis · Awareness · Provision · Patient groups

Introduction Overall HIV incidence in the United States (US) has remained stable since 2010, yet incidence rates have increased in some groups [1]. The use of daily oral pre-exposure prophylaxis (PrEP) has been proven highly effective in reducing HIV acquisition [2–5]. Although PrEP is highly effective, under 10% of persons with behavioral indications for PrEP have filled prescriptions [6, 7]. Numerous studies reported the awareness, attitudes, and prescribing practices of US providers, as well as their willingness to prescribe Electronic supplementary material  The online version of this article (https​://doi.org/10.1007/s1046​1-020-03089​-5) contains supplementary material, which is available to authorized users. * Jamal T. Jones [email protected] 1



Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop US8‑4, Atlanta, GA 30333, USA



Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA

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PrEP to groups with substantial risk for HIV acquisition [8–14]. Data from cross-sectional surveys assessing provider awareness, attitudes, and experiences with prescribing PrEP estimate that 86% to 93% of survey respondents were aware of PrEP, but only 9% to 39% of all respondents ever prescribed PrEP for the prevention of HIV [8–12]. Providers support the provision of PrEP and are willing to prescribe PrEP to persons with increased risk for HIV acquisiti