Precancerous Lesions of the Gynecologic Tract Diagnostic and Molecul
This volume provides a concise yet comprehensive overview of precancerous lesions and gynecologic tract cancers. Each section discusses the historic evolution of a precancerous lesion, its epidemiology, the nature of the published evidence that supports i
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Precancerous Lesions of the Gynecologic Tract
Oluwole Fadare Editor
Precancerous Lesions of the Gynecologic Tract Diagnostic and Molecular Genetic Pathology
Editor Oluwole Fadare Department of Pathology University of California San Diego San Diego, CA, USA
ISBN 978-3-319-22508-1 ISBN 978-3-319-22509-8 DOI 10.1007/978-3-319-22509-8
(eBook)
Library of Congress Control Number: 2015955576 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Many malignancies have a morphologically recognizable precursor lesion, a fact that at least theoretically offers the opportunity to intercept the malignancy before its development or to diagnose and treat it at an early stage. The cervix represents an enduring model for using precancerous lesion-centered screening and management programs to reduce the mortality and morbidity associated with a cancer. In the larger female genital tract, precancerous and putative precancerous lesions abound, and the past several years has seen the description of new lesions as well as an evolution in our diagnostic approach to, and understanding of, the long-existing ones. In this book, we aim to produce a comprehensive overview of precancerous lesions of the gynecologic tract, authored by an international group of authors well versed in the various areas. The chapters are arranged in broad, organ-based subsections that should facilitate their review. Contributors were encouraged to discuss lesions that are well established as precancerous lesions, such as the squamous intraepithelial neoplasms of the lower genital tract as precursors of squamous cell carcinomas at these sites, as well as the more newly reported putative precursors, such as atypical lobular endocervical glandular hyperplasia as a precursor
