Predictors of neo-aortic valve regurgitation in the long term after arterial switch operation

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ORIGINAL ARTICLE

Predictors of neo‑aortic valve regurgitation in the long term after arterial switch operation Takuma Takada1   · Seiji Asagai2   · Masaki Sato2 · Gen Harada2 · Eriko Shimada2 · Mikiko Ishido2 · Tokuko Shinohara2 · Kei Inai2 · Nobuhisa Hagiwara1 Received: 15 June 2020 / Accepted: 6 November 2020 © Springer Japan KK, part of Springer Nature 2020

Abstract Although arterial switch operations (ASOs) have been performed globally to repair d-transposition of the great arteries (d-TGA) in neonates and infants, few studies have been reported regarding the influence of the hemodynamics of patients with d-TGA who have undergone ASO on the development of neo-aortic valve regurgitation (AR). We aimed to investigate the relationship between the hemodynamics and development of AR after ASO in patients with d-TGA by catheter evaluation. This observational study screened 114 consecutive patients who underwent ASO for d-TGA or Taussig–Bing anomaly and who subsequently underwent catheter evaluations in our institution. We reviewed their records for the past 20 years and collected their first catheterization data post-ASO in early childhood. Thirty-six post-ASO patients who underwent catheter evaluations in both the early surgical and long-term phases were finally analyzed. Patients were divided into the following groups according to the presence of significant AR in the long-term phase: the AR group (n = 9 with AR ≥ grade II by the Sellers classification) and the non-AR group (n = 27 with AR