Preoperative anemia and total hospitalization time are the independent factors of preoperative deep venous thromboemboli
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RESEARCH ARTICLE
Open Access
Preoperative anemia and total hospitalization time are the independent factors of preoperative deep venous thromboembolism in Chinese elderly undergoing hip surgery Long Feng1,2, Longhe Xu3, Weixiu Yuan2, Zhipeng Xu3, Zeguo Feng3* and Hong Zhang1,3*
Abstract Background: This study was designed to explore the prevalence and risk factors of preoperative deep venous thromboembolism (DVT) in Chinese elderly with hip fracture. Methods: From January 1, 2012, to December 31, 2018, 273 elderly patients over 70 years old with elective hip surgery were collected from the electronic medical records. Collected data included demographic characteristics, comorbidities, ASA classification, types of previous operations, types of anesthesia, operation time, fracture to operation time, preoperative hemoglobin level, anemia, blood-gas analysis, cardiac function, whether transfusion, preoperative hospitalization, postoperative hospitalization, electrocardiograph, lower limb venous ultrasonography and total hospitalization time. Results: In these 273 patients, 15(5.6%) had ultrasonography evidence of DVT in affected limbs before surgery. Three of all patients received an temporary inferior vena cave filter placement preoperatively. Fracture to surgery time, preoperative hemoglobin level, anemia, preoperative hospitalization, pulmonary disease and total hospitalization time were statistically different between DVT group and non-DVT group (P < 0.05 for all). Moreover, preoperative anemia (OR: 0.144, 95%CI: 0.026– 0.799, P = 0.027) and total hospitalization time (OR: 1.135; 95%CI: 1.023–1.259, P = 0.017) were the two independent risk factors for preoperative DVT. Conclusion: Preoperative anemia and total hospitalization time were independent risk factors for venous DVT in Chinese elderly with hip fracture. Keywords: Anesthesia, Deep vein thrombosis, Hip fracture, Hospitalization time, Anemia
Background Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a serious and preventable complication after hip fracture [1–4]. * Correspondence: [email protected]; [email protected] 3 Department of Anesthesia Operation Center, Chinese PLA General Hospital, No.28, Fuxing Road, Beijing 100853, China 1 Medicine School of Chinese PLA, No.28, Fuxing Road, Beijing 100853, China Full list of author information is available at the end of the article
The risk for VTE among patients undergoing major orthopedic surgery, particularly hip fracture surgery, is the highest among all surgical patients. It has been reported that preoperative DVT had an incidence of 6–9% in patients with hip fracture receiving surgery within the 48 h, whereas the rate could be raised to 54.5–62% when there was a delay for more than 48 h [5]. Pedersen et al. [6] have proposed that hip fracture was associated with increased subsequent risk of VTE in a population-based cohort
© The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which p
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