Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease
- PDF / 906,605 Bytes
- 4 Pages / 595.276 x 790.866 pts Page_size
- 72 Downloads / 179 Views
Annals of Clinical Microbiology and Antimicrobials Open Access
SHORT REPORT
Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease Luis A. Marcos1,2*, Kalie Smith1, Kelsey Reardon1, Fredric Weinbaum3 and Eric D. Spitzer4
Abstract A series of cases in the Northeast of the US during 2013–2015 described a new Borrelia species, Borrelia miyamotoi, which is transmitted by the same tick species that transmits Lyme disease and causes a relapsing fever-like illness. The geographic expansion of B. miyamotoi in the US also extends to other Lyme endemic areas such as the Midwestern US. Co-infections with other tick borne diseases (TBD) may contribute to the severity of the disease. On Long Island, NY, 3–5% of ticks are infected by B. miyamotoi, but little is known about the frequency of B. miyamotoi infections in humans in this particular region. The aim of this study was to perform a chart review in all patients diagnosed with B. miyamotoi infection in Stony Brook Medicine (SBM) system to describe the clinical and epidemiological features of B. miyamotoi infection in Suffolk County, NY. In a 5 year time period (2013–2017), a total of 28 cases were positive for either IgG EIA (n = 19) or PCR (n = 9). All 9 PCR-positive cases (median age: 67; range: 22–90 years) had clinical findings suggestive of acute or relapsing infection. All these patients were thought to have a TBD, prompting the healthcare provider to order the TBD panel which includes a B. miyamotoi PCR test. In conclusion, B. miyamotoi infection should be considered in the differential diagnosis for flu-like syndromes during the summer after a deer tick bite and to prevent labeling a case with Lyme disease. Keywords: Borrelia miyamotoi, Lyme disease, Tick borne diseases, New York Background Suffolk County, a suburban county on Long Island (LI), New York, has a population of 1.8 million people and annually reports the highest absolute number of tickborne diseases in NY. In 2017, there were 523 cases of Lyme disease, 55 cases of Ehrlichiosis, 31 cases of Anaplasmosis, and 138 cases of Babesiosis [1]. A series of cases in the Northeast US described a new Borrelia species, Borrelia miyamotoi, first reported to cause human infections in 2013 [2]. B. miyamotoi is closely related to the relapsing fever family of Borrelia spp (e.g. B. hermsii); however, it is transmitted by Ixodes scapularis, the same tick that transmits Borrelia burgdorferi (Lyme disease), Anaplasma phagocytophilum and Babesia microti [3]. *Correspondence: [email protected] 1 Division of Infectious Diseases, Department of Internal Medicine, Stony Brook University, 101 Nicolls Rd, HSC16‑027 J, Stony Brook, NY 11794, USA Full list of author information is available at the end of the article
The geographic expansion of B. miyamotoi in the US extends to other Lyme endemic areas such as the Midwest of North America [4]. B. miyamotoi infection can clinically present during warm months as a flu-like syndrome similar to Lyme disease, Anaplasmosis, or Babesiosis. The d
Data Loading...
