Principles of Pulmonary Protection in Heart Surgery
Over the past fifty years, advanced techniques and strategies have been developed in the field of myocardial protection during heart surgery requiring cardiopulmonary bypass (CPB), but trials focusing on pulmonary protection have been less frequent. Princ
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%DMO!TIQUE'ABRIELs4OMAS!3ALERNO (Editors)
Principles of Pulmonary Protection in Heart Surgery
Dr. Edmo Atique Gabriel Federal University of Sao Paulo Sao Paulo Brazil
ISBN: 978-1-84996-307-7
Dr. Tomas A. Salerno University of Miami Miller School of Medicine Jackson Memorial Hospital Miami Florida USA
e-ISBN: 978-1-84996-308-4
DOI: 10.1007/978-1-84996-308-4 Springer Heidelberg Dordrecht London New York A catalogue record for this book is available from the British Library Library of Congress Control Number: 2010930085 © Springer-Verlag London Limited 2010 Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may only be reproduced, stored or transmitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency. Enquiries concerning reproduction outside those terms should be sent to the publishers. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore free for general use. Product liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Cover design: eStudio Calamar, Figueres/Berlin Printed on acid-free paper Springer Science+Business Media (www.springer.com)
This book is dedicated to God, to my parents Edmo Gabriel and Maria Lucia Atique Gabriel and my brother Sthefano Atique Gabriel. This book is dedicated to my wife Helen Salerno, my children Mark and Kim Salerno and to my parents José and Silveria F. Salerno. Edmo Atique Gabriel Tomas Salerno
Preface
Over the past fifty years, advanced techniques and strategies have arisen in the field of myocardial protection. Meticulous trials, focusing on pulmonary protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This textbook is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as an adjunct for minimizing the deleterious effects of pulmonary ischemia-reperfusion injury in heart surgery. Many renowned authors have contributed by presenting their experience on lung perfusion in basic research and clinical trials. Furthermore, they have enlightened the quality of this textbook with new ideas, concepts, and future perspectives. The scope of this textbook is of interest to different professionals, such as cardiovascular surgeons, pulmonary surgeons, transplantation physicians, cardiothoracic anesthesiologists, intensive care physicians, cardiothoracic fellows, radiologists, basic sci
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