Prognosis of patients with recurrence after pulmonary metastasectomy for colorectal cancer
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ORIGINAL ARTICLE
Prognosis of patients with recurrence after pulmonary metastasectomy for colorectal cancer Yasushi Sakamaki1 · Daisuke Ishida1 · Ryo Tanaka1 Received: 14 February 2020 / Accepted: 11 April 2020 © The Japanese Association for Thoracic Surgery 2020
Abstract Objectives We investigated the prognosis of patients with recurrence of pulmonary metastases (PM) from colorectal cancer (CRC) after resection. Methods We reviewed our surgical series of 101 CRC patients with PM who underwent R0 resection with curative intent. The overall survival (OS) and disease-free survival (DFS) rates after metastasectomy as well as the prognostic factors of survival were analyzed. Results Fifty-five patients (54%) experienced recurrence, of whom 21 had developed extrapulmonary metastasis (EPM) before lung resection. Multivariate analysis restricted to patients with recurrence identified a disease-free interval (DFI) shorter than a year as an adverse prognosticator of OS (HR, 2.68; 95% CI 1.40–5.51; P
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