Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection
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Journal of Translational Medicine Open Access
RESEARCH
Prognostic factors in patients admitted to an urban teaching hospital with COVID‑19 infection Donogh Maguire1* , Marylynne Woods2†, Conor Richards2†, Ross Dolan3, Jesse Wilson Veitch2, Wei M. J. Sim2, Olivia E. H. Kemmett2, David C. Milton2, Sophie L. W. Randall2, Ly D. Bui2, Nicola Goldmann2, Allan Cameron4, Barry Laird5,6, Dinesh Talwar7, Ian Godber8, Alan Davidson1 and Donald C. McMillan3
Abstract Background: Severe COVID-19 infection results in a systemic inflammatory response (SIRS). This SIRS response shares similarities to the changes observed during the peri-operative period that are recognised to be associated with the development of multiple organ failure. Methods: Electronic patient records for patients who were admitted to an urban teaching hospital during the initial 7-week period of the COVID-19 pandemic in Glasgow, U.K. (17th March 2020—1st May 2020) were examined for routine clinical, laboratory and clinical outcome data. Age, sex, BMI and documented evidence of COVID-19 infection at time of discharge or death certification were considered minimal criteria for inclusion. Results: Of the 224 patients who fulfilled the criteria for inclusion, 52 (23%) had died at 30-days following admission. COVID-19 related respiratory failure (75%) and multiorgan failure (12%) were the commonest causes of death recorded. Age ≥ 70 years (p
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