Progress in Molecular and Subcellular Biology
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.Progress in Molecular and Subcellular Biology With Contributions by st. Bram . P. Chandra' U. Ebener' H. Laube W. Lotz . D. Oesterhelt . R. A. Olsson R. E. Patterson' L. K. Steel' M. Sussman G. Will· H. J. Witmer' M. Woltersdorf
Editorial Board F. E. Hahn' H. Kersten' W. Kersten' T. T. Puck G. F. Springer' W. Szybalski . K. Wallenfels Managing Editor F. E. Hahn With 88 Figures
Springer-Verlag Berlin Heidelberg New York 1976
ISBN-13: 978-3-642-66251-5 e-ISBN-13: 978-3-642-66249-2 001: 10.1007/978-3-642-66249-2
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law where copies are made for other than private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with publisher. © by Springer-Verlag Berlin' Heidelberg 1976. Library of Congress Catalog Card Number 75-79748.
Softcover reprint of the hardcover 1st edition 1976 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
Twenty Five Years of Molecular Biology Fred E. Hahn
Molecular Biology has apparently come of age. The name was introduced into the modern scientific literature a quarter of a centuryago (ASTBURY, 1950). The Journal of Molecular Biology began its publication in 1959, followed by Molecular Pharmacology, Molekularnaia Biologiia, Molecular Photochemistry, Journal of Molecular and Cellular Biochemistry, Clinical Science and Molecular Medicine, Molecular and General Genetics, Molecular Etiology and probably other periodicals dedicated to molecular aspects of the life sciences whose titles may have escaped our cursory search. If one adds to this the numerous sets of monographs and review collections, including this series, the source and secondary literatures in molecular biology comprise, by now, a sizeable library. Molecular biology is, no doubt, a chemical science. However, during the past two decades it has become fashionable to substitute for the traditional adjective, biochemical, the more alluring "molecular". One author (KOSOWER, 1962) even published a treatise, entitled Molecular Biochemistry whose redundancy in title was commented upon by writing, "In the past few years, a new research area has emerged from the application of the physical-organic approach to the problem in chemical transformation found in biochemistry. We choose to call this area molecular biochemistry, and delimit it as the study of the detailed chemical mechanisms of the chemical transformations in biology, usually as they are described in biochemistry". Hence, underneath the molecular vogue in communicating biochemical research, there lives an expectation that the mechanics of
