Progressive Multiple Sclerosis
This revised, updated second edition draws together the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive
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Progressive Multiple Sclerosis
Second Edition
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Progressive Multiple Sclerosis
Alastair Wilkins Editor
Progressive Multiple Sclerosis Second Edition
Editor Alastair Wilkins Southmead Hospital University of Bristol Bristol United Kingdom
ISBN 978-3-319-65920-6 ISBN 978-3-319-65921-3 (eBook) https://doi.org/10.1007/978-3-319-65921-3 Library of Congress Control Number: 2017960800 © Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Since the first edition of Progressive Multiple Sclerosis, knowledge concerning the disease has advanced significantly. The drive for therapies to address disease progression is active and our understanding of the pathophysiology of the disease grows year on year. This has helped inform development of new treatments, and the hope is that the significant advances in relapsing and remitting disease will be replicated in progressive MS over the coming years. Importantly, the first successful clinical trials in progressive MS are being reported and a novel drug therapy approved and licenced. The second edition of Progressive Multiple Sclerosis is intended to update readers with an overview of the current state of knowledge concerning this common disease. The field is evolving and new concepts have arisen since the publication of the first edition. New chapters on novel therapies and rehabilitation have been added and existing chapters updated. It is hoped that this book will be of use to neurologists, both those in training and those who have practiced for many years. The book composes chapters covering the expanse of knowledge on progressive multiple scleros
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