Project 1: Stochastic Simulations
In this chapter, you will learn how to implement the Gillespie’s stochastic simulation algorithm (SSA) algorithm using G programming language—LabVIEW. You will be taught how to implement a simple irreversible reaction which, later on, you can extend furth
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Genetic Design Automation A Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits
Genetic Design Automation
Hasan Baig • Jan Madsen
Genetic Design Automation A Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits
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Hasan Baig Center for Quantitative Medicine, UConn Health University of Connecticut Connecticut, CT, USA
Jan Madsen Department of Applied Mathematics and Computer Science Technical University of Denmark (DTU) Lyngby, Denmark
ISBN 978-3-030-52354-1 ISBN 978-3-030-52355-8 (eBook) https://doi.org/10.1007/978-3-030-52355-8 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To our families.
Preface
In 1961, François Jakob and Jacques Monod, two pioneering French molecular biologists, speculated that gene regulating elements could in principle be combined to produce custom systems for control of genetic activity. Gene regulation is an essential mechanism for cell metabolism, which allows the cell to increase or decrease the production of specific proteins. As the production of one protein may be used to regulate the production of other proteins, cells contain sophisticated and often complex gene-regulatory networks to respond to various conditions, such as environmental stimuli, adapt to new food sources, or trigger developmental pathways. With the advent of DNA sequencing, it became possible for researchers to identify and classify gene regulating elements, effectively creating libraries of such elements or components. This allowed researchers to combine these components into novel configurations to modify existing properties or to create or synthesize entirely new
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