Prostate Biopsy Interpretation: An Illustrated Guide
Prostate needle biopsy specimens account for an important portion of a surgical pathologist’s daily work. There is, however, a significant error rate when diagnosing prostate cancer in needle biopsies. Furthermore, the modified Gleason grading scheme is b
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2AJAL"3HAHs-ING:HOU Authors
Prostate Biopsy Interpretation: An Illustrated Guide
!UTHORS Rajal B. Shah, M.D. Director, Urologic Pathology Caris Life Sciences 6655 North MacArthur Boulevard Irving, Texas 75039 USA [email protected]
Ming Zhou, M.D., Ph.D. Associate Professor Director of Surgical Pathology, Tisch Hospital Director of Genitourinary Pathology, Tisch Hospital New York University 550 First Avenue New York, NY 10016 USA [email protected]
ISBN 978-3-642-21368-7 e-ISBN 978-3-642-21369-4 DOI 10.1007/978-3-642-21369-4 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2011937719 © Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudioCalamar, Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
To my wife, Ami Shah, and sons Ansh and Alay, for their unconditional love, support, and constantly reminding me that there is life beyond work. To my parents, Bipin Shah and Sharmishtha Shah, for their genes, sacrifice, and motivation. Rajal B. Shah, M.D. To my wife, Lan Zhou, and daughters Grace and Rebecca, for their unwavering support. Ming Zhou, M.D., Ph.D.
Preface
This book is the product of a prostate biopsy course that we taught at several national pathology meetings over a period of 5 years. After the lectures, attendees of different levels – residents, fellows, pathologists in private practice and academia – came to us to compliment the practicality and timeliness of our course and encouraged us to turn it into a handy reference book. When Melissa Ramondetta, Executive Editor at Springer, approached us for writing a book on prostate biopsy, we enthusiastically agreed to her proposal. Prostate needle biopsy specimens constitute a significant portion of a surgical pathologist’s daily work. However, prostate biopsy specimens are not every pathologist’s darling. There is a significant error rate on diagnosing prostate cancer in needle biopsy,
