Prostate Cancer Imaging: An Ongoing Change of Paradigm
For decades, accurate detection of prostate cancer foci within the gland has been considered impossible. As a result, protocols of systematically distributed prostate biopsies have been used to investigate patients with clinical suspicion of prostate canc
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Management of Prostate Cancer A Multidisciplinary Approach Second Edition
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Management of Prostate Cancer
Michel Bolla • Hendrik van Poppel Editors
Management of Prostate Cancer A Multidisciplinary Approach Second Edition
Editors Michel Bolla Department of Radiation Oncology Hôpital Albert Michallon Grenoble France
Hendrik van Poppel Department of Urology University Hospitals Leuven Leuven Belgium
ISBN 978-3-319-42768-3 ISBN 978-3-319-42769-0 (eBook) DOI 10.1007/978-3-319-42769-0 Library of Congress Control Number: 2016963566 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Prostate cancer is the first ranked cancer in men in Europe. Despite the 10-year overall survival improvement provided by the ERSPC, there is no European mass screening as for breast or colon and rectum cancers, but early diagnosis is possible among men aged 50–75 years managed by general practitioners and/or urologists provided an informed consent is obtained, taking into account age, family history of cancer, co-morbidity, baseline PSA, prostate volume, PSA density and velocity, as well as information about biopsy modalities and potential side effects. Random biopsies become more precise thanks to the matching of magnetic resonance imaging and ultrasound acquisitions to guide them on the index lesion. Once clinical workup is done, TNM and d’Amico classifications are established, the medical charts of the patients are discussed in tumour board and individualized treatments are proposed according to national and/or EAU guidelines to be explained later on to the patients. Phase III randomized trials have contributed to set up a multidisciplinary approach between pathologists, urologists, radiation oncologists and
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