Quality-of-life evaluation for patients submitted to nasal endoscopic surgery for resection of pituitary tumours
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RHINOLOGY
Quality‑of‑life evaluation for patients submitted to nasal endoscopic surgery for resection of pituitary tumours Ricardo Landini Lutaif Dolci1,2,4 · Lígia Tédde de Moraes1 · Ana Carolina Mayor de Carvalho1 · Jeniffer Cristina Kozechen Rickli1 · Jamile Lopes de Souza1 · Williams Escalante Encinas3 · José Viana Lima Junior2,5 · Nilza Maria Scalissi2,5 · Américo Rubens Leite dos Santos2,3,4 · Paulo Roberto Lazarini1,2,4 Received: 24 May 2020 / Accepted: 15 September 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose This study aimed to evaluate the pre- and post-operative quality-of-life of patients submitted to the resection of pituitary adenoma via endoscopic transsphenoidal. Methods This was a prospective study on patients submitted to endoscopic transsphenoidal pituitary surgery with the harvest of a nasoseptal flap who responded to the questionnaires FV-36 and SNOT-22 in the pre-operative and in months 1, 3 and 6 following the surgical procedure. Results A total of 42 patients submitted to pituitary adenoma resection surgery via endoscopic transsphenoidal with a nasoseptal flap were recruited. In all of the physical and mental domains (SF-36) evaluated, there was an improvement in the long-term evaluation (6 months), compared to the pre-operative, as well as in the site-specific evaluation (SNOT-22). Conclusion The global and site-specific questionnaires in the 6th post-operative month follow-up presented an important improvement in all the physical and mental domains evaluated, as well as in nasal function in the perception of the patients submitted to pituitary adenoma resection via endoscopic transsphenoidal, demonstrating the safety and efficiency of the procedure. Keywords Skull base · Quality-of-life · Pituitary adenoma · Patient health questionnaire · Hypophyse
Introduction The World Health Organization defines quality-of-life (QoL) as “the perception by the individual of his or her insertion in life in the context of culture and values systems he or she lives in and in relation to his or her objectives, expectations, * Ricardo Landini Lutaif Dolci [email protected] 1
Otolaryngology Departament, Santa Casa de Misericórdia of São Paulo, R. Dr. Cesário Mota Jr, 112‑Pavilhão Conde de Lara, 4º andar, São Paulo, SP, Brazil
2
Medical Sciences College at Santa Casa de SP, São Paulo, Brasil
3
Neurosurgery Discipline, Surgery Departament, Santa Casa de Misericórdia of São Paulo, São Paulo, SP, Brazil
4
Skull Base Surgery Nucleus at Santa Casa of São Paulo, São Paulo, SP, Brazil
5
Endocrinology and Metabology Discipline, Santa Casa de Misericórdia of São Paulo, São Paulo, SP, Brazil
standards and concerns”. It is a multidimensional concept which considers a minimum of four dimensions: physical, social, psychological and functional [1]. The evaluations of QoL are applied to analyze the modalities of treatment for a disease, aiming at promoting those which lead to a better restoration of daily life activities, as well as a smaller impact on th
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