Quasispecies: From Theory to Experimental Systems
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness l
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Esteban Domingo Peter Schuster Editors
Quasispecies: From Theory to Experimental Systems
Current Topics in Microbiology and Immunology Volume 392
Series editors Rafi Ahmed School of Medicine, Rollins Research Center, Emory University, Room G211, 1510 Clifton Road, Atlanta, GA 30322, USA Klaus Aktories Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Abt. I, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany Richard W. Compans Department of Microbiology and Immunology, Emory University, 1518 Clifton Road, CNR 5005, Atlanta, GA 30322, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, GA 30322, USA Jorge E. Galan Boyer Ctr. for Molecular Medicine, School of Medicine, Yale University, 295 Congress Avenue, room 343 New Haven, CT 06536-0812, USA Tasuku Honjo Faculty of Medicine, Department of Medical Chemistry, Kyoto University, Sakyo-ku, Yoshida, Kyoto 606-8501, Japan Yoshihiro Kawaoka Influenza Research Institute, University of Wisconsin-Madison, 575 Science Drive, Madison, WI 53711, USA Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288, Marseille Cedex 9, France Michael B.A. Oldstone Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla CA 92037, USA Rino Rappuoli Novartis Vaccines, Via Fiorentina 1, Siena, 53100, Italy Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA 92037, USA Honorary Editor: Hilary Koprowski (deceased) Formerly at Biotechnology Foundation, Inc., Ardmore, PA, USA
More information about this series at http://www.springer.com/series/82
Esteban Domingo Peter Schuster •
Editors
Quasispecies: From Theory to Experimental Systems Responsible Series Editor: Michael B.A. Oldstone
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Editors Esteban Domingo Centro de Biología Molecular Severo Ochoa (CSIC-UAM) Campus de Cantoblanco Madrid Spain
Peter Schuster Institut für Theoretische Chemie Universität Wien Vienna Austria and The Santa Fe Institute Santa Fe, NM USA
ISSN 0070-217X ISSN 2196-9965 (electronic) Current Topics in Microbiology and Immunology ISBN 978-3-319-23897-5 ISBN 978-3-319-23898-2 (eBook) DOI 10.1007/978-3-319-23898-2 Library of Congress Control Number: 2016930545 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, e
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