Radiation therapy for resistant sternal hydatid disease
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· H. Barut1 · M. Tunc1 · E. Aydin2 · E. Aydınkarahaliloğlu1 · A. Gokcek3 · N. Karaoğlanoğlu2 1 Department of Radiation Oncology, Ataturk Chest Disease and
Thorasic Surgery Training and Research Hospital, Ankara 2 Department of Thorasic Surgery, Ataturk Chest Disease and Thorasic
Surgery Training and Research Hospital, Ankara 3 Department of Radiology, Ataturk Chest Disease and Thorasic
Surgery Training and Research Hospital, Ankara
Radiation therapy for resistant sternal hydatid disease Introduction Hydatid disease is a zoonotic infectious disease seen mostly in the liver, but which can develop anywhere in the body, such as the mediastinum, pleura, diaphragm, and central nervous system [1]. It is a considerable public health problem caused by the larval stage of the Echinococcus tapeworm [2]. There are known treatment procedures and effective antibiotics against hydatid disease; however, surgical procedures are commonly required if lesions are localized on bone. Rarely, hydatid bone cysts cannot be controlled despite repeated surgery, a situation in which radiation therapy represents a good alternative treatment procedure for refractory osseous hydatidosis. Against this background, we report a new case of hydatid disease of the chest that has been treated with radiation therapy after multiple surgical procedures and medical treatment had failed.
in the lung parenchyma on chest computed tomography (CT). A biopsy specimen of the sternal mass revealed a diagnosis of Echinococcus multilocularis infection. Albendazole treatment was started immediately. Although the parenchymal lesions regressed, no response was seen in the sternal lesions. The patient underwent repeat surgical procedures in 2004, 2007, and 2008. All histopathological examinations revealed a granulomatous reaction and cavitary lesions that were histochemically positive for PAS staining. The patient’s symptoms of pain increased 1 year after the previous surgery. Chest CT showed a cystic and lytic lesion invading and extending the sternum, to-
Case report A 62-year-old man was admitted to the authors’ center in October 2009 complaining of pain and tenderness in the chest wall accompanied by a history of recurrent chest disease since 2004. He was initially diagnosed with a cystic mass invading the sternum and bilateral cystic lesions
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Strahlentherapie und Onkologie 6 · 2013
Fig. 1 7 A cystic and lytic lesion destroying and extending the sternum
gether with extrapleural soft tissue lesions (. Fig. 1). The decision was taken to administer radiation therapy (RT). The authors prescribed an external beam radiation dose of 25 Gy (250 cGy/day, 5 days/ week) by linear accelerator with 3D conformal radiation, encompassing radiographically visible lesions. At 1-year follow-up, the patient was free of chest pain and his disease was stable. However, a speech impairment and loss of balance subsequently developed. Cranial CT showed a cystic lesion on the left frontal lobe and the patient underwent surgery. He recovered well from brain surgery and was fr
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