Reflections on treatment of COVID-19 with traditional Chinese medicine
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Chinese Medicine Open Access
REVIEW
Reflections on treatment of COVID‑19 with traditional Chinese medicine Hua Luo†, Yan Gao†, Jian Zou, Siyuan Zhang, Hanbin Chen, Qiao Liu, Dechao Tan, Yan Han, Yonghua Zhao* and Shengpeng Wang*
Abstract Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional Chinese medicine (TCM) and western medicine, China has achieved good clinical efficacy in the prevention and control of the pandemic. The advantages of TCM in the treatment of COVID-19 include effective relief of symptoms, retarding the development from mild and moderate to severe, improvement of cure rate, reducing death rates, and promotion of rehabilitation. Besides, according to the different severity levels of individual cases, the National Health Commission of the People’s Republic of China issued treatment guidelines that provide corresponding prescriptions for patients. From the perspective of TCM, this review aims to analyze the role of a variety of TCM prescriptions in the treatment of COVID-19, focusing on the analysis of the “Three TCM prescriptions and three medicines” recommended by the Chinese authorities during the pandemic. We expect that this review will provide insights into the prevention and treatment of COVID-19 with TCM. Keywords: COVID-19, Coronavirus, Traditional Chinese medicine, Prescriptions Background Coronavirus disease 2019 (COVID‑19) belongs to “plague” in the concept of traditional Chinese medicine (TCM), which refers to the virulent infectious diseases with the etiology of epidemic factors [1]. In Chinese his‑ tory, TCM has battled against hundreds of epidemic/ pandemic events, which accumulated a store of effective therapeutic experiences and methods. For instance, in the Song dynasty (960-1279 AD), Chinese practitioners fought against smallpox by variolation. During the battle against SARS in 2003, China leveraged the advantages of TCM and achieved excellent curative outcomes by inte‑ grating TCM and western medicine. In the treatment of COVID-19, TCM have also showed favorable effects in amelioration of pathological evolution, and the high cure
*Correspondence: [email protected]; [email protected] † Hua Luo and Yan Gao contributed equally to this work Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China
rate and low mortality in China were highly appreciated by the World Health Organization (WHO). On Jan 22, 2020, the National Health Commission (NHC) of the People’s Republic of China firstly recom‑ mended TCM for the priority treatment of COVID-19 and included four syndromes and corresponding formu‑ lae in the Diagnosis and Treatment Protocol for COVID19 (Trial Version 3). Subsequently, in Trial Version 4 and 5, the prototype of Huashi Baidu Formula (化濕敗毒方) was gradually developed for treating the syndrome of pestilent toxin blocking lung (疫毒閉肺), and got mature in Trial Version 6 and 7. Simultaneous
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