Regenerative Medicine for Degenerative Muscle Diseases
This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters naviga
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Martin K. Childers Editor
Regenerative Medicine for Degenerative Muscle Diseases
Stem Cell Biology and Regenerative Medicine
Series Editor Kursad Turksen, Ph.D. [email protected]
More information about this series at http://www.springer.com/series/7896
Martin K. Childers Editor
Regenerative Medicine for Degenerative Muscle Diseases
Editor Martin K. Childers Department of Rehabilitation Medicine University of Washington Seattle, WA, USA Institute for Stem Cell and Regenerative Medicine, School of Medicine University of Washington Seattle, WA, USA
ISSN 2196-8985 ISSN 2196-8993 (electronic) Stem Cell Biology and Regenerative Medicine ISBN 978-1-4939-3227-6 ISBN 978-1-4939-3228-3 (eBook) DOI 10.1007/978-1-4939-3228-3 Library of Congress Control Number: 2015956772 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Humana Press is a brand of Springer Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
Preface
Regenerative medicine—an emerging multidisciplinary field composed of clinicians, bioengineers, pharmacologists, surgeons, and others—seeks to develop new ways of repairing and replacing cells, tissues, and organs. A great example of regenerative medicine technology was pioneered by Anthony Atala, MD, who pioneered the world’s first urinary bladder made from the patient’s own cells and grown in a laboratory before being implanted into the patient. This process of regenerative medicine differs radically from conventional medicine by not only treating symptoms but by recreating damaged tissues and organs in the human body. Unthinkable only a few years ago, clinicians and scientists are rapidly exploiting nature’s secrets to replace damaged tissue or to stimulate the body’s own natural repair mechanisms to heal previously irreparable tissues or organs. For degenerative muscle diseases, thi
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