Regulation mechanism of biomolecule interaction behaviors on the superlubricity of hydrophilic polymer coatings
- PDF / 2,322,079 Bytes
- 16 Pages / 595.22 x 842 pts (A4) Page_size
- 4 Downloads / 124 Views
ISSN 2223-7690 CN 10-1237/TH
RESEARCH ARTICLE
Regulation mechanism of biomolecule interaction behaviors on the superlubricity of hydrophilic polymer coatings Caixia ZHANG1,2, Junmin CHEN1, Mengmeng LIU2, Yuhong LIU3, Zhifeng LIU1,2, Hongyan CHU1,2,*, Qiang CHENG2, Jianhua WANG1,2 1
Institute of Advanced Manufacturing and Intelligent Technology, Beijing University of Technology, Beijing 100124, China
2
Beijing Key Laboratory of Advanced Manufacturing Technology, Beijing University of Technology, Beijing 100124, China
3
State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China
Received: 18 April 2020 / Revised: 09 June 2020 / Accepted: 10 August 2020
© The author(s) 2020. Abstract: Hydrophilic polymer coatings can improve the surface characteristics of artificial implants. However, because they are used in vivo, they inevitably come into contact with biomolecules that affect their interfacial tribological properties. In this paper, the friction behaviors of poly(vinylphosphonic acid) (PVPA)-modified Ti6Al4V and polytetrafluorethylene balls were analyzed using albumin, globulin, aggrecan, and hyaluronic acid as lubricants. The interaction properties and dynamic adsorption characteristics of the biomolecules and PVPA molecules were explored by a quartz crystal microbalance to identify the cause of the friction difference. It was found that protein molecules disturbed the superlubricity of the PVPA−phosphate-buffered saline system because of the formation of a stable adsorption film, which replaced the interfacial characteristics of the PVPA coating. Polysaccharides, with their excellent hydration properties and polymer structure, had an unstable dynamic interaction or zero adsorption with PVPA molecules, and hardly changed the superlubricity of the PVPA and phosphate-buffered-saline system. The influence mechanism of the specific friction of proteins and polysaccharides was analyzed. Interactions were observed among different biomolecules. Polysaccharides can potentially reduce protein adsorption. The result of the synergistic regulation of the friction coefficient for PVPA-modified Ti6Al4V is approximately 0.017. The results of this study will provide a theoretical basis for the use of polymer coatings in vivo. Keywords: superlubricity; hydrophilic polymer; protein; polysaccharide
1
Introduction
Artificial implants can help restore the functional movement/mobility of people suffering from joint disease or recovering from an accident. Current biomaterials research on artificial implants has focused on the improvement of wear resistance, such as metallic, polymeric, ceramic, and novel biomimetic materials and potential combinations of materials to extend the life of the implant [1]. Titanium alloy is one of the most widely used materials in artificial
joints because of its excellent biocompatibility and good mechanical strength [2−4]. However, its applications are limited by their low wear resistance [5]. Attempts have been made to improve the tribological properties of titanium alloys. I
Data Loading...
