Reproducibility of strain and twist measurements calculated using CSPAMM tagging
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POSTER PRESENTATION
Open Access
Reproducibility of strain and twist measurements calculated using CSPAMM tagging Peter Swoboda1*, Abdulghani Larghat2, John Greenwood2, Sven Plein2 From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Objective To establish inter-observer and inter-study variability of CSPAMM (complementary spatial modulation of magnetization) tagged CMR data. Background The reproducibility of CSPAMM-derived myocardial strain and left ventricular twist have not been described in detail.
strain between the two operators was 6.9% (2.3), 8.2% (7.7) and 6.7% (5.0) at apex, mid-LV and base respectively. There was no significant difference in inter-observer variability in endocardial, midline and epicardial contours. See Table 1 for Co-V results. Mean (SD) difference in mid-myocardium circumferential strain between visits was 6.7% (4.1), 6.5% (4.0) and 8.8 % (5.2) at apex, mid-LV and base respectively. Mean (SD) difference in radial strain between operators was 28.1% (47.8), 17.6% (21.6) and 26.7% (25.6) and
Methods 12 healthy volunteers (6 males, mean age 33±7 years) underwent CMR studies on a 1.5T system (Intera CV, Philips Healthcare, The Netherlands). Tagged CMR images were acquired at the apex, mid-ventricle and base with a CSPAMM pulse sequence (field of view: 300mm, matrix 128 x 128, slice thickness 10mm, tag separation 8mm, 18 phases, typical TR/TE 30ms/6ms, flip angle 25 degrees). In 6 volunteers repeat data sets were acquired after a mean interval of 8±3 days. Data were analysed by two independent observers using Tagtrack software (Gyrotools, CH). Circumferential Langranian strain, radial Langranian strain and rotation were calculated for the three short axis slices. Endocardial and epicardial borders were drawn, and a midline calculated automatically. Left ventricular twist was calculated by subtracting the basal rotation from the apical rotation. The mean difference between paired measurements, the standard deviation (SD) of the differences and the coefficient of variability (Co-V) were calculated. Results Circumferential strain increased from base to apex (Figure 1a). Mean (SD) difference in circumferential 1
Leeds General Infirmary, Leeds, UK Full list of author information is available at the end of the article
Figure 1 Figure 1a shows circumferential strain measured by observers A & B. Figure 1b shows rotation measured by observers A & B and calculated left ventricular twist.
© 2011 Swoboda et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Swoboda et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):P52 http://jcmr-online.com/content/13/S1/P52
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Table 1 shows percentage difference and coefficient of variation (Co-V) for inter-observer and inter-study variability of measu
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