Risk factors of in-hospital death in patients with acute ST elevation myocardial infarction
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CE-RESEARCH LETTER TO THE EDITOR
Risk factors of in‑hospital death in patients with acute ST elevation myocardial infarction Yong Li1 Received: 27 March 2020 / Accepted: 6 April 2020 © The Author(s) 2020
Keywords Coronary disease · ST elevation myocardial infarction · In-hospital mortality · Killip classification
Background
Evaluation and diagnosis of in‑hospital death
Coronary heart disease remains the leading cause of mortality [1]. Prevention of in-hospital death is a crucial step in improving prognosis of patients with ST elevation myocardial infarction (STEMI). We want to investigate the risk factors of in-hospital death.
All causes for in-hospital death is defined as cardiac or noncardiac death during hospitalization.
Methods Source of data Totally 9668 patients with acute STEMI in Beijing Anzhen Hospital, Capital Medical University from January 2002 to August 2019. Inclusion criteria: (1) patient hospitalized with STEMI; (2) age of more than 18 years. We established the diagnosis of acute myocardial infarction (AMI) and STEMI base on fourth universal definition of myocardial infarction [2]. Exclusion criteria: none.
We registered this study with WHO International Clinical Trials Registry Platform (ICTRP) (registration number: ChiCTR1900027129; registered date: 1 November 2019). https:// www.chictr.org.cn/edit.aspx?pid=44888&htm=4 Electronic supplementary material The online version of this article (https://doi.org/10.1007/s11739-020-02338-8) contains supplementary material, which is available to authorized users. * Yong Li [email protected] 1
Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
Predictors We selected 11 predictor variables for inclusion in our prediction rule. They were shown in Table 1. PCI = percutaneous coronary intervention, CABG = coronary artery bypass grafting. Atrial fibrillation is defined as all type of atrial fibrillation during hospitalization. Atrioventricular block is defined as all type of atrioventricular block during hospitalization.
Statistical analysis We followed the methods of Li et al. 2019 [3].
Results Participants and predictors of in‑hospital death Totally 188 patients had in-hospital death (in-hospital death group) and 9480 patients had no in-hospital death (control group). The results are shown in Table 1.
Predictors of in‑hospital death Eight variables (age, gender, history of myocardial infarction, history of hypertension, Killip classification, atrial fibrillation, atrioventricular block, and underwent PCI during hospitalization) were significant differences in the two groups of patients (p
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