Risk of congenital heart disease due to exposure to common electrical appliances during early pregnancy: a case-control
- PDF / 282,407 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 4 Downloads / 159 Views
RESEARCH ARTICLE
Risk of congenital heart disease due to exposure to common electrical appliances during early pregnancy: a case-control study Doudou Zhao 1,2 & Leqian Guo 1,3 & Ruo Zhang 1,4 & Qixia Zhu 1 & Hongli Wang 1 & Rong Liu 1 & Hong Yan 1 & Shaonong Dang 1 Received: 4 April 2019 / Accepted: 14 September 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract To examine the association between exposure to common electrical appliances in early pregnancy and congenital heart disease (CHD). A case-control study of 2339 participants was conducted in six hospitals in Xi’an, Shaanxi Province, Northwest China from 2014 to 2016. All infants with CHD were diagnosed according to ICD-10 classification. Selected controls consisted of newborns from the same hospital, without any birth defects, and 1:3 matched by birthdate. We conducted personal interviews with the mothers to gather information on any exposure to electrical appliances during pregnancy. Multivariate logistic regression was used to estimate the effects of exposure to common electrical appliances on CHD. We observed that the mothers exposed to computers (OR: 1.33, 95% CI: 1.03, 1.71), induction cookers (OR: 2.79, 95% CI: 2.19, 3.55), and microwave ovens (OR: 1.53, 95% CI: 1.01, 2.31) during early pregnancy were more likely to give birth to infants with CHD. Mothers who wore radiation protection suits (OR: 0.67, 95% CI: 0.52, 0.87) during early pregnancy decreased the risk of CHD in their neonate. There was an interaction for induction cooker exposure with wore radiation protection suits on CHD (RERI: − 1.44, 95% CI: − 2.48, − 0.39; S: 0.37, 95% CI: 0.16, 0.84; AP: − 0.79, 95% CI: − 1.53, − 0.05). Our study confirmed that exposure to some electrical appliances was associated with a higher risk of CHD, and wearing a radiation protection suit was associated with a lower risk of CHD. Women should therefore reduce the usage of electrical appliances before and during pregnancy. Keywords Congenital heart disease . Common electrical appliances . Case-control study
Hong Yan and Shaonong Dang contributed equally to this work. Responsible Editor: Philippe Garrigues * Hong Yan [email protected]
Hongli Wang [email protected]
* Shaonong Dang [email protected]
Rong Liu [email protected]
Doudou Zhao [email protected] Leqian Guo [email protected] Ruo Zhang [email protected] Qixia Zhu [email protected]
1
Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi, China
2
Department of Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an 710061, Shaanxi, China
3
Department of Obstetrics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China
4
Department of Endocrinology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China
Environ Sci Pollut Res
Background
Methods
Congenital heart disease (CHD) is a cardiovascular malformation resulting from abnormal f
Data Loading...
