Role of Chymase in Matrix and Myocardial Remodeling Due to Mitral Regurgitation: Implications for Therapy
The pure volume overload of mitral regurgitation (MR) has many unique features including matrix metalloproteinase (MMP) activation, increased bradykinin, extracellular matrix loss, disruption of the focal adhesion complex, and cardiomyocyte myofibrillar l
- PDF / 9,463,351 Bytes
- 565 Pages / 439.37 x 666.14 pts Page_size
- 33 Downloads / 160 Views
Volume 1: S. K. Cheema (ed), Biochemistry of Atherosclerosis Volume 2: S. W. Schaffer and M-Saadeh Suleiman (eds), Mitochondria: The Dynamic Organelle Volume 3: A. K. Srivastava and M. B. Anand-Srivastava (eds), Signal Transduction in the Cardiovascular System in Health and Disease Volume 4: B. Ostadal and N. S. Dhalla (eds), Cardiac Adaptations-Molecular Mechanisms Volume 5: B. I. Jugdutt and N. S. Dhalla (eds), Cardiac Remodeling-Molecular Mechanisms
For further volumes: http://www.springer.com/series/7064
Bodh I. Jugdutt
•
Naranjan S. Dhalla
Editors
Cardiac Remodeling Molecular Mechanisms
Editors Bodh I. Jugdutt Walter MacKenzie Health Sciences Centre Division of Cardiology University of Alberta Edmonton, AB, Canada
Naranjan S. Dhalla St. Boniface Hospital Research Centre Institute of Cardiovascular Sciences Winnipeg, MB, Canada
ISBN 978-1-4614-5929-3 ISBN 978-1-4614-5930-9 (eBook) DOI 10.1007/978-1-4614-5930-9 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2013930229 © Springer Science+Business Media New York 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
This book is dedicated to my peers, colleagues, teachers, students, and friends who inspire and stimulate me in lifelong search for knowledge that can be applie
Data Loading...
