Safety and patient-reported outcomes in index ablation versus repeat ablation in atrial fibrillation: insights from the

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ORIGINAL PAPER

Safety and patient‑reported outcomes in index ablation versus repeat ablation in atrial fibrillation: insights from the German Ablation Registry Shinwan Kany1 · Johannes Brachmann2 · Thorsten Lewalter3 · Karl‑Heinz Kuck4 · Dietrich Andresen5 · Stephan Willems6 · Ellen Hoffmann7 · Lars Eckardt8 · Dierk Thomas9 · Matthias Hochadel10 · Jochen Senges10 · Andreas Metzner1 · Andreas Rillig1 Received: 20 July 2020 / Accepted: 12 October 2020 © The Author(s) 2020

Abstract Background  Pulmonary vein isolation is an established strategy for catheter ablation of atrial fibrillation (AF). However, in a significant number of patients, a repeat procedure is mandatory due to arrhythmia recurrence. In this study, we report safety data and procedural details of patients undergoing index ablation versus repeat ablation in a registry-based real-life setting. Methods  Patients from the German Ablation Registry, a prospective, multicentre registry of patients undergoing ablation between January 2007 and January 2010 were included. Results  A total of 4155 patients were enrolled in the study. Group I (index ablation) consisted of 3377/4155 (82.1%) and group II (repeat ablation) of 738/4155 (17.9%). Patients in group I had a significantly higher ratio of paroxysmal AF (69.3% vs 61.9%, p