Salivary Bioscience and the Future of Behavioral Medicine
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SPECIAL ISSUE: SALIVARY BIOSCIENCE
Salivary Bioscience and the Future of Behavioral Medicine Michael A. Hoyt 1,2
&
Douglas A. Granger 2
# International Society of Behavioral Medicine 2020
Abstract Behavioral medicine research from across the globe has been catalyzed by the quest to understand the interactions between psychological, social, and physiological factors underlying disparities in human health. A more complete biopsychosocial model increasingly integrates advanced clinical and laboratory assessments of relevant environmental chemicals, biological mediators of inflammation, cardiometabolic and endocrine markers, infectious disease exposure, and genetic polymorphisms determined from saliva specimens. The overarching aims are to identify mechanisms, decode moderating processes that translate adversity into risk, and verify the impact of clinical intervention. This special issue of the International Journal of Behavioral Medicine highlights novel contributions of salivary bioscience with emphasis on research utilizing varied research designs (i.e., experimental, longitudinal, dyadic), incorporating a broad array of salivary analytes, and investigating the influence of psychological and social factors on human health. Keywords Salivary bioscience . Behavioral medicine
Introduction Over the past few decades, behavioral medicine researchers have been empowered by minimally invasive means of monitoring biological and physiological processes using oral fluids as a biospecimen (see [1] for review). Advances in technology have allowed evaluation of individual differences between, and changes within, individuals’ physiological processes in ways not accessible in the past. These tools enable repeated measurement of the physiological components of interacting biobehavioral processes in the laboratory and, more importantly, in the context of everyday life (e.g., home, work, school, play) and among communities in which collecting traditional biospecimens would be prohibitive due to societal or cultural norms. Such designs have aided in understanding complex stress dynamics, behavioral influences on disease processes, the mechanisms of health disparities,
* Michael A. Hoyt [email protected] 1
Population Health and Disease Prevention and the Chao Family Comprehensive Cancer Center, University of California Irvine, 653 E Peltason Drive, Irvine, CA 95697-3957, USA
2
Interdisciplinary Institute for Salivary Bioscience Research, University of California Irvine, Irvine, CA, USA
and how to optimize behavioral interventions to benefit health. Across behavioral medicine, applying these new technologies underscores the importance of context as a determinant of the expression of biological variables and as a moderator of relationships between biological processes and healthrelevant outcomes. Correspondingly, salivary bioscience has ushered in advances not only in measurement but also in conceptual modeling and analytical strategies and tactics required to test those models [2]. The purpose of this special issue of the Intern
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