Scoping review: hotspots for COVID-19 urological research: what is being published and from where?

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Scoping review: hotspots for COVID‑19 urological research: what is being published and from where? Liang G. Qu1,2,3   · Marlon Perera1,2 · Nathan Lawrentschuk2,4,5 · Rainy Umbas6 · Laurence Klotz7 Received: 26 June 2020 / Accepted: 30 August 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  Contemporary, original research should be utilised to inform guidelines in urology relating to the COVID-19 pandemic. This comprehensive review aimed to: identify all up-to-date original publications relating to urology and COVID-19, characterise where publications were from, and outline what topics were investigated. Methods  This review utilised a search strategy that assessed five electronic databases, additional grey literature, and global trial registries. All current published, in-press, and pre-print manuscripts were included. Eligible studies were required to be original research articles of any study design, reporting on COVID-19 or urology, in any of study population, intervention, comparison, or outcomes. Included studies were reported in a narrative synthesis format. Data were summarised according to primary reported outcome topic. A world heatmap was generated to represent where included studies originated from. Results  Of the 6617 search results, 48 studies met final inclusion criteria, including 8 pre-prints and 7 ongoing studies from online registries. These studies originated from ten countries according to first author affiliation. Most studies originated from China (n = 13), followed by Italy (n = 12) and USA (n = 11). Topics of the study included pathophysiological, administrative, and clinical fields: translational (n = 14), COVID-19-related outcomes (n = 5), urology training (n = 4), telemedicine (n = 7), equipment and safety (n = 2), urology in general (n = 4), uro-oncology (n = 3), urolithiasis (n = 1), and kidney transplantation (n = 8). Conclusion  This review has outlined available original research relevant to COVID-19 and urology from the international community. This summary may serve as a guide for future research priorities in this area. Keywords  COVID-19 · Urology · Uro-oncology · Training · Telemedicine · Kidney transplantation Abbreviations ACE2 Angiotensin-converting enzyme II ADT Androgen-deprivation therapy AKI Acute kidney injury CI Confidence interval COVID-19 Coronavirus 19 Electronic supplementary material  The online version of this article (https​://doi.org/10.1007/s0034​5-020-03434​-2) contains supplementary material, which is available to authorized users. * Liang G. Qu [email protected] 1



Olivia Newton John Cancer Research Institute, Austin Health, Melbourne, VIC, Australia

2



Department of Surgery, University of Melbourne, Melbourne, VIC, Australia

3

Department of Urology, Austin Health, Heidelberg, VIC, Australia



EAU European Association of Urology ICU Intensive care unit OR Odds ratio PPE Personal protective equipment pRCC​ Papillary renal cell carcinoma RNA Ribonucleic acid SARS-CoV-2 Severe acute r