Secukinumab
- PDF / 169,326 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 78 Downloads / 152 Views
1 S
Interstitial lung disease as a paradoxical reaction: case report A 61-year-old man developed interstitial lung disease as a paradoxical reaction during treatment with secukinumab for psoriatic arthritis. The man had been receiving adalimumab for psoriatic arthritis with a good response for 9 years. However, his arthritis began to progress. Therefore, his treatment was switched to secukinumab [route and dosages not stated]. A good clinical response was noted. However, he developed a persistent cough, shortness of breath on exertion and blood-stained secretions. A CT thorax showed florid bibasal, lingula and middle lobe ground glass density air space opacification. Bronchoalveolar lavage was negative for atypical infection. Microscopy of bronchoalveolar lavage showed lymphocytosis. A diagnosis of interstitial lung disease as a paradoxical reaction to secukinumab was made [duration of treatment to reaction onset not stated]. Therefore, the man’s treatment with secukinumab was discontinued. Eventually, a significant improvement was noted. Saleh C, et al. Interstitial pneumonitis induced by secukinumab therapy in a patient with psoriatic arthritis. Rheumatology 59 (Suppl. 2): ii35-ii36 abstr. P45, Apr 2020. 803507416 Available from: URL: http://doi.org/10.1093/rheumatology/keaa111.044 [abstract]
0114-9954/20/1826-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 17 Oct 2020 No. 1826
Data Loading...
