Selenoproteins and Mimics

Selenium has a long history of association with human health and disease. This essential trace element exerts its important biological role in selenoproteins. "Selenoproteins and Mimics" presents the latest developments in selenoproteins, their functional

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ADVANCED TOPICS IN SCIENCE AND TECHNOLOGY IN CHINA Zhejiang University is one of the leading universities in China. In Advanced Topics in Science and Technology in China, Zhejiang University Press and Springer jointly publish monographs by Chinese scholars and professors, as well as invited authors and editors from abroad who are outstanding experts and scholars in their fields. This series will be of interest to researchers, lecturers, and graduate students alike. Advanced Topics in Science and Technology in China aims to present the latest and most cutting-edge theories, techniques, and methodologies in various research areas in China. It covers all disciplines in the fields of natural science and technology, including but not limited to, computer science, materials science, life sciences, engineering, environmental sciences, mathematics, and physics.

Junqiu Liu Guimin Luo Ying Mu

Selenoproteins and Mimics With 120 figures, 28 of them in color

Editors Prof. Junqiu Liu State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, China E-mail: [email protected]

Prof. Guimin Luo Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, 130012, China E-mail: [email protected]

Prof. Ying Mu Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, 310058, China E-mail: [email protected]

ISSN 1995-6819 e-ISSN 1995-6827 Advanced Topics in Science and Technology in China ISBN 978-7-308-08273-0 Zhejiang University Press, Hangzhou ISBN 978-3-642-22235-1 e-ISBN 978-3-642-22236-8 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2011930726 © Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

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Foreword

The research area of selenoproteins has seen considerable progress in recent years. The initial identification of selenium as an essential trace element was followed by the characterization