Self and Nonself
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recog
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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University of Pennsylvania RODOLFO PAOLETTI, University of Milan
Recent Volumes in this Series Volume 730 THE EFFECTS OF NOISE ON AQUATIC LIFE Anthony Hawkins and Arthur Popper Volume 731 SODIUM CALCIUM EXCHANGE Lucio Annunziato and Simina Calin Volume 732 REPRODUCTIVE HEALTH AND CANCER IN ADOLESCENTS AND YOUNG ADULTS Gwendolyn P. Quinn and Susan T. Vadaparampil Volume 733 NANO BIOTECHNOLOGY FOR BIOMEDICAL AND DIAGNOSTICS RESEARCH Eran Zahavy, Arie Ordenlich, Shmuel Yitzhaki and Avigdor Shafferman Volume 734 SYSTEMS BIOLOGY OF TUMOR DORMANCY Heiko Enderling, Nava Almog and Lynn Hlatky Volume 735 CURRENT TOPICS IN COMPLEMENT III John D. Lambris Volume 736 ADVANCES IN SYSTEMS BIOLOGY Igor I. Goryanin and Andrew B. Goryachev Volume 737 OXYGEN TRANSPORT TO TISSUE XXXIII Martin Wolf, Hans Ulrich Bucher, Markus Rudin, Sabine Van Huffel, Ursula Wolf, Duane F. Bruley, David K. Harrison Volume 738 SELF AND NONSELF Carlos López-Larrea
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
Self and Nonself Edited by Carlos López-Larrea, PhD Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
Springer Science+Business Media, LLC Landes Bioscience
Springer Science+Business Media, LLC Landes Bioscience Copyright ©2012 Landes Bioscience and Springer Science+Business Media, LLC All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing
and executed on a computer system; for exclusive use by the Purchaser of the work. Printed in the USA. Springer Science+Business Media, LLC, 233 Spring Street, New York, New York 10013, USA http://www.springer.com Please address all inquiries to the publishers: Landes Bioscience, 1806 Rio Grande, Austin, Texas 78701, USA Phone: 512/ 637 6050; FAX: 512/ 637 6079 http://www.landesbioscience.com The chapters in this book are available in the Madame Curie Bioscience Database. http://www.landesbioscience.com/curie Self and Nonself, edited by Carlos López-Larrea. Landes Bioscience / Springer Science+Business Media, LLC dual imprint / Springer series: Advances in Experimental Medicine and Biology. ISBN: 978-1-4614-1679-1 of equipment and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, t
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