Serous Cavity Fluid and Cerebrospinal Fluid Cytopathology

Cytologic diagnosis by examination of exfoliated cells in serous cavity fluids is one of the most challenging areas in clinical cytopathology. Almost 20% of the effusions examined are directly or indirectly related to the presence of malignant disease, wi

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ESSENTIALS IN CYTOPATHOLOGY SERIES Dorothy L. Rosenthal, MD, FIAC, Series Editor Editorial Board

Syed Z. Ali, MD Douglas P. Clark, MD Yener S. Erozan, MD

For further volumes: http://www.springer.com/series/6996

Syed Z. Ali Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA

Edmund S. Cibas Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Serous Cavity Fluid and Cerebrospinal Fluid Cytopathology

Syed Z. Ali Department of Pathology The Johns Hopkins Hospital 600 N. Wolfe Street Baltimore, MD 21287, USA [email protected]

Edmund S. Cibas Department of Pathology Brigham and Women’s Hospital Harvard Medical School 75 Francis Street Boston, MA 02115, USA [email protected]

ISSN 1574-9053 e-ISSN 1574-9061 ISBN 978-1-4614-1775-0 e-ISBN 978-1-4614-1776-7 DOI 10.1007/978-1-4614-1776-7 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011943105 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

Serous cavity and cerebrospinal spinal fluids are among the most challenging areas in the practice of cytopathology. Familiarity with the variety of cytomorphological features of specific conditions, along with awareness of the overlapping features of some benign and malignant diseases, is essential to meet these challenges. In this book, the authors provide a comprehensive yet concise presentation of the cytomorphology and differential diagnoses of various conditions as well as the ancillary techniques which help to establish an accurate diagnosis. A brief description of clinical features and preparation techniques, the basic requirements for an optimal cytopathologic diagnosis, are also included. The cytopathology of serous cavity fluids is presented in nine chapters. Emphasis is placed on areas of potential diagnostic problems. Ample clinical information is given, as is