Short- and long-term outcomes of laparoscopic versus open lateral lymph node dissection for locally advanced middle/lowe

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and Other Interventional Techniques

Short‑ and long‑term outcomes of laparoscopic versus open lateral lymph node dissection for locally advanced middle/lower rectal cancer using a propensity score‑matched analysis Jun Watanabe1   · Atsushi Ishibe2 · Yusuke Suwa1 · Mayumi Ozawa2 · Kazuya Nakagawa2 · Hirokazu Suwa3 · Mitsuyoshi Ota1 · Chikara Kunisaki1 · Itaru Endo2 Received: 14 May 2020 / Accepted: 25 August 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Background  There are few reports on large-scale trials for the long-term outcomes regarding laparoscopic lateral lymph node dissection (LLND). We evaluated the short- and long-term outcomes of laparoscopic versus open LLND for locally advanced middle/lower rectal cancer using a propensity score-matched analysis. Methods  From January 2005 to December 2016, consecutive clinical stage II to III middle/lower rectal cancer patients who underwent total mesorectal excision (TME) plus LLND were retrospectively collected at three institutions. Laparoscopic LLND was compared with open LLND for the surgical and oncological outcomes, including the long-term survival, using a propensity score-matched analysis. Results  A total of 325 patients were collected. There were 142 patients who underwent open TME plus LLND (open group) and 183 patients who underwent laparoscopic TME plus LLND (laparoscopic group). A total of 93 patients each were matched to each group. Compared to the open group, the laparoscopic group had a significantly longer operative time (327 vs. 377 min; p = 0.002) but significantly less blood loss (540 vs. 50 ml; p