Single-incision versus conventional multiport laparoscopic cholecystectomy: a current meta-analysis of randomized contro

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and Other Interventional Techniques

Single‑incision versus conventional multiport laparoscopic cholecystectomy: a current meta‑analysis of randomized controlled trials Yunxiao Lyu1,2   · Yunxiao Cheng1 · Bin Wang1 · Sicong Zhao1 · Liang Chen1 Received: 27 June 2019 / Accepted: 9 October 2019 © Springer Science+Business Media, LLC, part of Springer Nature 2019

Abstract Background  We performed this study to compare the safety and feasibility of single-incision laparoscopic cholecystectomy (SILC) with conventional multiple-port laparoscopic cholecystectomy (MPLC). Methods  We searched PubMed, Embase, Web of Science, the Cochrane Controlled Register of Trials (CENTRAL), and ClinicalTrials.gov for randomized controlled trials comparing SILC versus MPLC. We evaluated the pooled outcomes for complications, pain scores, and surgery-related events. This study was performed in accordance with PRISMA guidelines. Results  A total of 48 randomized controlled trials involving 2838 patients in the SILC group and 2956 patients in the MPLC group were included in this study. Our results showed that SILC was associated with a higher incidence of incisional hernia (relative risk = 2.51; 95% confidence interval = 1.23–5.12; p = 0.01) and longer operation time (mean difference = 15.27 min; 95% confidence interval = 9.67–20.87; p