Sleep-Disordered Breathing and Postoperative Outcomes After Bariatric Surgery: Analysis of the Nationwide Inpatient Samp

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ORIGINAL CONTRIBUTIONS

Sleep-Disordered Breathing and Postoperative Outcomes After Bariatric Surgery: Analysis of the Nationwide Inpatient Sample Babak Mokhlesi & Margaret D. Hovda & Benjamin Vekhter & Vineet M. Arora & Frances Chung & David O. Meltzer

# Springer Science+Business Media New York 2013

Abstract Background Sleep-disordered breathing (SDB), also known as obstructive sleep apnea (OSA), has been increasingly recognized as a possible risk factor for adverse perioperative outcomes in non-bariatric surgeries. However, the impact of SDB on postoperative outcomes in patients undergoing bariatric surgery remains less clearly defined. We hypothesized that SDB would be independently associated with worse postoperative outcomes. Methods Data were obtained from the Nationwide Inpatient Sample database and included a total of 91,028 adult patients undergoing bariatric surgeries from 2004 to 2008. The primary outcomes were in-hospital death, total charges, and length of stay. There were two secondary outcomes of interest: respiratory and cardiac complications. Regression models were fitted to assess the independent association between SDB and the outcomes of interest. B. Mokhlesi (*) : M. D. Hovda Sleep Disorders Center and the Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, 5841 S. Maryland Ave MC6076, Chicago, IL 60637, USA e-mail: [email protected] B. Vekhter : V. M. Arora : D. O. Meltzer Center for Health and Social Sciences, The University of Chicago, Chicago, IL, USA V. M. Arora Section of General Internal Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA F. Chung Department of Anesthesia, University Health Network, University of Toronto, Toronto, ON, Canada D. O. Meltzer Section of Hospital Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA

Results SDB was independently associated with decreased mortality (OR=0.34, 95% CI=0.23–0.50, p