Solitary fibrous tumor of the liver: a case report

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WORLD JOURNAL OF SURGICAL ONCOLOGY

CASE REPORT

Open Access

Solitary fibrous tumor of the liver: a case report Ke Sun1, Jian-Ju Lu2, Xiao-Dong Teng1, Li-Xiong Ying1 and Jian-Feng Wei2*

Abstract Hepatic solitary fibrous tumor (SFT) is a rare tumor originating from the mesenchyme. Here we report a new case of SFT in the liver and review the clinical presentation, radiological and operative findings, diagnosis, treatment, and outcome. The patient was a 59-year-old man who presented with progressive fatigue for 3 months and an abdominal mass for 3 days. On laboratory tests, no abnormality was detected except that abdominal ultrasonography revealed a 9.0 × 6.2 cm hypoechogenic mass in the left lobe of the liver. A computed tomographic scan confirmed a hypodense lesion in the left lobe of the liver. The patient underwent left hepatectomy. SFT was diagnosed on the basis of histopathological findings. The patient was free from all symptoms and had no signs of local recurrence after 24 months’ follow up. Background Solitary fibrous tumor (SFT) is a rare spindle-cell neoplasm of mesenchymal origin, first described by Klemperer and Robin in the visceral pleura in 1931 [1]. It usually is found in the thoracic cavity and pleura, but, rarely, it can involve other organs such as the mediastinum [2], the skin [3], soft tissue [4], the thyroid gland [5], the orbit [6], and others. Although most solitary fibrous tumors have benign behavior, some may have malignant features such as metastasis and recurrence. Clinical or radiological findings are not specific and cannot exclude malignancy. Preoperative cytology may be inconclusive or misleading. Currently, the prevailing view is that immunohistology, including CD34 and vimentin, should be used to precisely diagnose SFT [7]. The outcome of an SFT of the liver is mostly related to resectability [8]. Thus, complete surgical removal of the neoplasm is most commonly proposed. We report a case of SFT of the liver and review the literature to date. Case Presentation A 59-year-old man was admitted to our hospital because of progressive fatigue for 3 months and an abdominal mass for 3 days. The patient had no history of viral hepatitis. Laboratory tests, including routine biochemistry, liver function, and tumor markers, were normal. * Correspondence: [email protected] 2 Department of Hepatobiliary Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, Zhejiang, 310003, PR China Full list of author information is available at the end of the article

A plain chest X-ray was normal. Abdominal ultrasonography revealed a 9.0 × 6.2 cm hypoechogenic mass in the left lobe of the liver. Computed tomography (CT) demonstrated a large heterogeneous circumscribed mass in the left hepatic lobe and contrast enhancement in the arterial and portal phases (Figure 1A, B, C). Left hepatectomy was performed, and the patient recovered without complications. Grossly, the tumor was a large, gray-white, lobulated, well-circumscribed partially encapsulated mass, m