Special Topics in Brain Metastases Management
Several sites of metastases near or within the brain require special consideration because of their neuroanatomical location, proximity to critical organs, or particularly poor prognosis. Many of these sites are not considered surgically accessible, nor e
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Radiotherapy in Managing Brain Metastases
Yoshiya Yamada • Eric Chang John B. Fiveash • Jonathan Knisely Editors
Radiotherapy in Managing Brain Metastases A Case-Based Approach
Editors Yoshiya Yamada Department of Radiation Oncology Memorial Sloan Kettering Cancer Center New York, NY USA
Eric Chang Department of Radiation Oncology University of Southern California Los Angeles, CA USA
John B. Fiveash Department of Radiation Oncology University of Alabama at Birmingham Birmingham, AL USA
Jonathan Knisely Weill Cornell Medicine NewYork–Presbyterian Hospital New York, NY USA
ISBN 978-3-030-43739-8 ISBN 978-3-030-43740-4 (eBook) https://doi.org/10.1007/978-3-030-43740-4 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
Galileo and Michelangelo. Hippocrates and the Beatles. There is science and there is art. There are scientists and there are artists. This textbook is the best of both. Much of the science is new, and the integrated application of that science is the art. The focus of their science and art is one of the most rapidly evolving topics in oncology today – brain metastases. This topic transcends any one type of cancer. While in the past this diagnosis was under-researched because of the incorrect conventional wisdom that all such patients held the same dismal prognosis, we now understand the vast heterogeneity among this patient population. We are now able to peek over the horizon at the dawn of a new era in which this heterogeneity holds clues that will lead us far beyond local control of an individual tumor to a future in which a systemic response may be ignited by the application of modern therapies in proper sequence
