sQuiz your knowledge: Violaceous plaque-like lesions on the dorsum
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A 42-year-old male, with no relevant previous medical history, presented to our centre with multiple violaceous
plaque-like lesions on the dorsum, that were tender and painful on palpation (figure 1). The condition was present since birth, with lesions increasing in number and size over time. No involvement of the mucosa was identified, and he denied any related systemic symptoms. When inquired about family history, it was revealed that his sixyear-old son had similar small nodules on the forearms and legs.
What is your likely diagnosis?
Figure 1. Tender, violaceous plaque-like lesions on the dorsum.
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EJD, vol. 30, n◦ 4, July-August 2020
Glomuvenous malformations (GVM) Glomuvenous malformations (GVM), previously known as glomangiomas, are an uncommon subset of venous malformation (VM), characterized by distinct histopathology, clinical presentation and association with loss-of-function mutations in the glomulin gene (GLMN) [1]. Classically, they occur as painful, bluish solitary papules, widely scattered nodules or segmental plaques that are frequently hyperkeratotic and may assume a cobblestone-like appearance. In contrast to classic VM, GVM are often present at birth, and increase in size slowly during childhood. They rarely affect the mucosa, viscera or joints and a positive family history is present in approximately two thirds of the patients [2]. While skin biopsy is not always required for diagnosis, histopathology of GVM demonstrates venous-like channels surrounded by glomus cells, which stain positive for vimentin and ␣-smooth muscle actin and negative for desmin [1, 3]. Treatment options in selected cases include sclerotherapy, laser therapy and surgical excision [1]. Disclosure. Financial support: none. Conflicts of interest: none.
sQuiz your knowledge: a recurrent annular erythema Li-wen ZHANG1,a , Yan LIU1,a , Dong-xian LIU2 1
Department of Dermatovenereology, Chengdu Second People’s Hospital, Chengdu, Sichuan, China 2 Department of Dermatovenereology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China a These authors contributed equally. [email protected] [email protected]
A 24-year-old man presented with a one-year history of recurrent itchy annular erythematous lesion on the back. Two weeks ago, the lesion began to appear as a single erythematous lesion with some papules, which then expanded centrifugally. An annulus with hyperpigmentation then developed in the centre (figure 1A). The ring of the annular lesion was composed of papules and erythema (figure 1B). The same lesion had appeared over the same site one year earlier, resolving spontaneously within a month. The fungal microscopy was negative. A skin biopsy was taken from the peripheral erythema, and papules and histopathological results showed a sparse perivascular lymphocytic infiltration in the superficial dermis (figure 1C).
References What is your diagnosis? 1. Moreno-Arrones OM, Jimenez N, Alegre-Sanchez A, et al. Glomuvenous malformations: dual PDL-Nd:YAG laser approac
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