Strategies for Immunointerventions in Dermatology
Recent progress in the fields of pharmacology and immunology has provided us with new possibilities for treating dermatological diseases. This book reviews the most important immunosuppressive and immunostimulatory drugs and gives helpful, practical infor
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Gunter Burg Reinhard G. Dummer (Eds.)
Strategies for Immunointerventions in Dermatology With 35 Figures und 22 Tables
Springer
Burg, Gunter, Prof. Dr. Chairman of the Department of Dermatology University Hospital Zurich Gloriastrasse 31 CH -8091 Zurich, Switzerland Dummer, Reinhard G., PD Dr. Department of Dermatology University Hospital Zurich Gloriastrasse 31 CH -8091 Zurich, Switzerland
Sponsored by an educational grant from Novartis Pharma Schweiz AG
Library of Congress Cataloging-in· Publication Data Strategies for immunointerventions in dermatology 1 Giinter Burg, Reinhard Dummer (eds.). p. cm. Includes bibliographical references and index. ISBN-13: 978-3-642-64539-6 e-ISBN-13: 978-3-642-60752-3 DOl: 10.1007/978-3-642-60752-3 I. Skin-Diseases-Immunological aspects. 2. Dermatopharmacology. 3. Immunopharmacology. I. Burg, Giinter. II. Dummer, Richard, 1960RL97.S77 1997 616.5'061-dc21 This work is subject to copyright. All rights reserved, whether the whole or part of the material is concerned, specifically the rights of translations, reprinting, reuse of illustrations, recitating, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts therof is only permitted under the provisions of the German Copyright Law of September 9, 1965, in its current version, and a copyright fee must always be paid. Violations fall under the prosecution act of the German Copyright Law. © Springer-Verlag Berlin Heidelberg 1997
Softcover reprint of the hardcover 1st edition 1997 The use of registered names, trademarks, etc. in this publication does not imply, even in the absende of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product Liability: The publishers can give no guarentee for information about drug dosage and applications therof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Production and Supervision: w. Bischoff, Heidelberg Cover Design: Design & Production, Heidelberg Typesetting and Reproduction of Figures: Renner Typografie & Satz, Wiesenbach SPIN: 10554459 23/3134 - 5432 1 0 - Printed on acid-free paper
Preface
The skin provides the structural and functional prerequisites for an array of cellular and humoral immune reactions assocoiated with a broad spectrum of dermatoses. Depend-ing on the type of disease, immunosuppresive or immunostimulatory therapeutic strategies may offer specific and well-tolerated treatment modalities. This book gives an updated overview - which is necessarily incomplete - of those substances and drugs currently in use which show immunostimulatory or immunosuppressive effects. The use of these substances is described from a clinician's point of view for various indications, such as autoimmune diseases, and neoplasias in parti
