Successful Revascularization has a Significant Impact on Limb Salvage Rate and Wound Healing for Patients with Diabetic
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CLINICAL INVESTIGATION
ARTERIAL INTERVENTIONS
Successful Revascularization has a Significant Impact on Limb Salvage Rate and Wound Healing for Patients with Diabetic Foot Ulcers: Single-Centre Retrospective Analysis with a Multidisciplinary Approach Anto´nio Proenc¸a Caetano1,2,3 • Ineˆs Conde Vasco1,2 • Filipe Veloso Gomes2,3 Nuno Vasco Costa2,3 • Jose´ Hugo Luz2,3 • Erik Spaepen4 • Ana Formiga5 • E´lia Coimbra6 • Jose´ Neves7 • Tiago Bilhim2,3
•
Received: 16 May 2020 / Accepted: 21 July 2020 Ó Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2020
Abstract Purpose Analyze the impact of endovascular revascularization on major amputation rates and wound healing for patients with diabetic foot ulcers (DFUs). Materials and Methods Single-center retrospective study from 2014–2018 including 314 patients with DFUs submitted to endovascular revascularizations. Group A—patients with a successful endovascular revascularization
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00270-020-02604-4) contains supplementary material, which is available to authorized users.
(n = 285; 90.8%); Group B—patients submitted to a failed attempt of endovascular revascularization (n = 29; 9.2%). Baseline data were not significantly different between the 2 groups (p [ 0.05). Both groups were compared regarding: major amputation rates; wound healing, mortality and adverse events. Survival and regression analyses were used. Results Mean follow-up time was 734.1 ± 610.2 days. Major amputation rates were 3.9% versus 24.1% (p \ 0.0001) and complete wound healing was 53.7% versus 20.7% (p \ 0.0001) for patients from Group A versus Group B, respectively. Major adverse events were 1
Centro Hospitalar Universita´rio de Lisboa Central (CHULC), 1069-166 Lisbon, Portugal
2
Ineˆs Conde Vasco [email protected]
Interventional Radiology Unit, Hospital Curry Cabral, Centro Hospitalar Universita´rio de Lisboa Central (CHULC), 1069-166 Lisbon, Portugal
3
Filipe Veloso Gomes [email protected]
Nova Medical School, Faculdade de Cieˆncias Me´dicas, Universidade Nova de Lisboa, Lisbon, Portugal
4
SBD Analytics, Bekkevoort, Belgium
5
Diabetic Foot Unit, Hospital Curry Cabral, Centro Hospitalar Universita´rio de Lisboa Central (CHULC), 1069-166 Lisbon, Portugal
6
Head Interventional Radiology Unit, Hospital Curry Cabral, Centro Hospitalar Universita´rio de Lisboa Central (CHULC), 1069-166 Lisbon, Portugal
7
Head of Diabetic Foot Unit, Hospital Curry Cabral, Centro Hospitalar Universita´rio de Lisboa Central (CHULC), 1069-166 Lisbon, Portugal
& Tiago Bilhim [email protected] Anto´nio Proenc¸a Caetano [email protected]
Nuno Vasco Costa [email protected] Jose´ Hugo Luz [email protected] Erik Spaepen [email protected] Ana Formiga [email protected] E´lia Coimbra [email protected] Jose´ Neves [email protected]
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A. Caetano et al: Successful Revascularization has a
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