Sugar Chains Decoding the Functions of Glycans
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as canc
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ar Chains
Decoding the Functions of Glycans
Sugar Chains
Tadashi Suzuki • Kazuaki Ohtsubo Naoyuki Taniguchi Editors
Sugar Chains Decoding the Functions of Glycans
Editors Tadashi Suzuki Glycometabolome Team, Systems Glycobiology Research Group RIKEN-Max-Planck Joint Research Center for Systems Chemical Biology RIKEN Global Research Cluster Wako, Saitama, Japan
Kazuaki Ohtsubo Department of Analytical Biochemistry Faculty of Life Sciences Kumamoto University Kumamoto, Japan
Naoyuki Taniguchi Disease Glycomics Team, Systems Glycobiology Research Group RIKEN-Max-Planck Joint Research Center for Systems Chemical Biology RIKEN Global Research Cluster Wako, Saitama, Japan
ISBN 978-4-431-55380-9 ISBN 978-4-431-55381-6 DOI 10.1007/978-4-431-55381-6
(eBook)
Library of Congress Control Number: 2015931251 Springer Tokyo Heidelberg New York Dordrecht London © Springer Japan 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer Japan KK is part of Springer Science+Business Media (www.springer.com)
Preface
When the title of this book, Sugar Chains, was first proposed by the publisher, for a moment I thought that it may sound a bit too non-scientific, but after pondering it, I found that this may be a perfect title for the book, as it somewhat reflects how glycoscience or glycobiology has been perceived by those who are non-experts. It is just an enigmatic “sugar” thing (in a strict sense, it actually represents sucrose!) attached to lipids or proteins that gives all of us, whether experts or not, a headache because of its incredible structural diversity as well as the lack of simple analytical methods. It has been more than two decades since the word “glycobiology” was coined. While this research area, due to its unique methodology not compatible with most biochemists, has long been regarded as a very specialized field with limited interest, the recent explosive research progress has provided countless examples of critical roles for glycan
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