Superficial Keratitis
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Monographs In Ophthalmology 1
Dr. W. JUNK bv PUBLISHERS THE HAGUE - BOSTON - LONDON
Superficial Keratitis Edited by
P.c. MAUDGAL and L. MISSOTTEN The Ey e Research Laboratory and the OphThalmological Clinic CaTholic University of Leuven. Belgium
Dr. W. JUNK bv PUBLISHERS THE HAGUE - BOSTON - LONDON
REPRINTED FROM Bull. Soc. beige Ophtal. 187-1, 1980
Distributors :
for the United States and Canada Kluwer Boston Inc. 190 Old Derby Street Hingham, MA 02043 USA
for all other countries Kluwer Academic Publishing Group Distribution Center P.O. Box 322 3300 AH Dordrecht The Netherlands
ISBN-13: 978-94-009-8673-2 DOl: 10.1 007/978-94-009-8671-8
e-ISBN-13: 978-94-009-8671 -8
Copyright © 1981 Belf(ian Society of Ophthalmology, Leuven, Belgium and Soficover reprint of the hardcover in 1st edition 1981 All rights reserved. No part of this publication may be reproduced stored in a retrival system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without the prior permission of the publishers. Dr. W. Junk bv Publishers, P.O. Box 13713, 2501 ES The Hague, The Netherlands.
CONTENTS Page
IV
Preface Chapter I. Diagnostic techniques in superficial keratitis Scrapings and smears Cultures Corneal replicas
1 1 2 2
Chapter II. The cornea Tear film Epithelium Stroma Descemet's membrane Endothelium
7 8 11 17 17 18
Chapter III. Healing of the epithelium Sliding of cells Mitosis Regeneration of basement membrane
19 19 24 25
Chapter IV. Corneal erosions Multiple punctate erosions Recurrent erosions Persistent epithelial defects
29 29 29 36
Chapter V.
Filamentary keratitis
41
Chapter VI. Fine punctate epithelial keratitis Warts Molluscum contagiosum
49 49
Chapter VII. Coarse punctate keratitis Adenoviral keratoconjunctivitis Pharyngoconjunctival fever Epidemic keratoconjunctivitis Chlamydial keratoconjunctivitis Trachoma Inclusion conjunctivitis Thygeson's superficial punctate keratitis
59 59
Chapter VIII. The herpes virus Herpes simplex Herpes zoster
54
61 63
70 71
78 81
93 93 128
Page
Chapter IX. The dry eye syndrome Dry spots Keratoconjunctivitis sicca
151 154 157
Chapter X. Marginal keratitis Staphylococcal blepharoconjunctivitis Superior limbic keratoconjunctivitis
179 179 180
Chapter XI.
Management of superficial keratitis
187
PREFACE In its long series of annual reports, the Belgian Society of Ophthalmology has a tradition of bringing into focus the recent advances in ophthalmology. But it seems surprising that one has to go back to 1940 to find a major report on the corneal diseases, when R. Rubbrecht wrote an "Aperr;u de la pathologie et de la therapeutique generale des maladies de la cornee". However, this omission is only apparent. In fact, many reports, since then, have contributed to our knowledge of the advances in corneal research. The corneal dimensions were documented in "La biometrie oculaire clinique (Y. Delmarcelle et aI., 1976)", the fine structure of the cornea in "L'ultrastructure de tissues oculaires (L. Missotten, 1964)", and
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