Surgical Treatment of Colorectal Liver Metastases

Surgery is the gold standard treatment of colorectal liver metastases. Patient management has undergone dramatic changes in recent years: more accurate diagnostic tools and more effective chemotherapy regimens have been introduced and surgical indications

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Lorenzo Capussotti (Ed.)

Surgical Treatment of Colorectal Liver Metastases In collaboration with Alessandro Ferrero Andrea Muratore Dario Ribero Luca Viganò

Forewords by Enrico De Antoni Gennaro Nuzzo

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Editor Lorenzo Capussotti Chief of the Surgical Department Director of the Division of Hepato-Bilio-Pancreatic and Digestive Surgery Mauriziano “Umberto I” Hospital Turin, Italy In collaboration with Alessandro Ferrero Andrea Muratore Dario Ribero Luca Viganò Division of Hepato-Bilio-Pancreatic and Digestive Surgery Mauriziano “Umberto I” Hospital Turin, Italy

The publication and the distribution of this volume have been supported by the Italian Society of Surgery

ISBN 978-88-470-1808-2

e-ISBN 978-88-470-1809-9

DOI 10.1007/978-88-470-1809-9 Springer Milan Dordrecht Heidelberg London New York Library of Congress Control Number: 2010933718 © Springer-Verlag Italia 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the Italian Copyright Law in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the Italian Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: Simona Colombo, Milan, Italy Typesetting: Graphostudio, Milan, Italy Printing and binding: Arti Grafiche Nidasio, Assago (MI), Italy Printed in Italy Springer-Verlag Italia S.r.l. – Via Decembrio 28 – I-20137 Milan Springer is a part of Springer Science+Business Media (www.springer.com)

Foreword

The management of colorectal liver metastases is one of the most rapidly changing areas in medicine. Over the last few decades, diagnostic imaging has tremendously improved, surgical indications and techniques have rapidly evolved, and newer and effective chemotherapies have expanded the armamentarium of medical oncologists. These achievements have, in turn, compelled physicians to redefine existing treatment strategies in recognition of the possibility of cure in patients who just a few years ago were deemed to have incurable disease. The restless work of innovative surgeons has established the value of an aggressive surgical attitude and has brought about a profound revision of long-standing criteria of resectability. New techniques have been developed, overcoming many of the previou