Surgical Treatment of Dystonia

Neurosurgical operations for the treatment of dystonia patients comprise extracerebral and intracerebral procedures. Several retrospective studies using selective peripheral denervation and selective myotomy for the treatment of patients with cervical dys

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Dystonia and Dystonic Syndromes

Petr Kanovsky • Kailash P. Bhatia Raymond L. Rosales Editors

Dystonia and Dystonic Syndromes

Editors Petr Kanovsky Department of Neurology Palacky University Medical School University Hospital Olomouc Olomouc Czech Republic

Raymond L. Rosales Department of Neurology and Psychiatry The Royal and Pontifical University of Santo Tomas Manila Philippines

Kailash P. Bhatia Sobell Department of Motor Neuroscience and Movement Disorders University College London Institute of Neurology London United Kingdom

ISBN 978-3-7091-1515-2 ISBN 978-3-7091-1516-9 DOI 10.1007/978-3-7091-1516-9

(eBook)

Library of Congress Control Number: 2015937625 Springer Wien Heidelberg New York Dordrecht London © Springer-Verlag Wien 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher's location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer-Verlag GmbH Wien is part of Springer Science+Business Media (www.springer.com)

Contents

Part I 1

Pathophysiology and Nosology of Dystonia

Dystonia: The Syndrome, Its Term, Concept and Their Evolution. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Petr Kanovsky, Raymond L. Rosales, and Kailash P. Bhatia

3

2

Physiology of Dystonia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Giovanni Abbruzzese, Elisa Pelosin, and Laura Avanzino

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3

Genetics of Dystonia . . . .