Survivors of Childhood and Adolescent Cancer A Multidisciplinary App
It was not long ago that clinicians would say,“study ed at the 1975 meeting revealed. Among them was the late complications of cancer treatments we give to one based on data collected by the Late Effects Study children? You must be joking! We can start wo
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Cindy L. Schwartz · Wendy L. Hobbie Louis S. Constine · Kathleen S. Ruccione (Eds.)
Survivors of Childhood and Adolescent Cancer A Multidisciplinary Approach Second Edition With 49 Figures and 61 Tables
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Library of Congress Control Number 2005920312 ISBN 3-540-40840-1 Springer Berlin Heidelberg NewYork ISSN 1613-5318 Originally published in 1994 by Mosby-Year Book, Inc., St. Louis, Missouri, USA Title: Survivors of Childhood Cancer: Assessment and Management
Cindy L. Schwartz
The Sidney Kimmel Cancer Center at Johns Hopkins Johns Hopkins Hospital 600 North Wolfe Street Baltimore, MD 21287-5001 USA Phone: 410-955-7385 E-mail: [email protected]
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media
Wendy L. Hobbie
springeronline.com
Childrens Hospital of Philadelphia Division of Oncology 34th St. & Civic Ctr. Blvd. Philadelphia, PA 19104 USA E-mail: [email protected]
© Springer-Verlag Berlin Heidelberg 2005 Printed in Germany
Louis S. Constine
Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature.
University of Rochester Medical Center Radiation Oncology and Pediatrics 601 Elmwood Avenue/Box 647 Rochester, NY 14642 USA E-mail: [email protected] Kathleen S. Ruccione
Childrens Hospital Los Angeles Center for Cancer and Blood Diseases 4650 Sunset Boulevard Los Angeles, CA 90027 USA E-mail: [email protected]
The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
Medical Editor: Dr. Julia Heidelmann, Heidelberg, Germany Desk Editor: Meike Stoeck, Heidelberg, Germany Cover design: Erich Kirchner, Heidelberg, Germany Layout: Bernd Wieland, Heidelberg, Germany Production: Marina Litterer, ProEdit GmbH, Heidelberg, Germany Reproduction and typesetting: AM-productions GmbH, Wiesloch, Germany 21/3150 – 5 4 3 2 1 0 Printed on acid-free paper
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Dedication
To the memory of those children for whom our knowledge was insufficient; to those children who have been cured but must approach adult life with the residua of treatment; and to the children of the future who will benefit from scientific advances that may limit treatme
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