Synthetic Biology The technoscience and its societal consequences

Synthetic biology is becoming one of the most dynamic new fields of biology, with the potential to revolutionize the way we do biotechnology today. By applying the toolbox of engineering disciplines to biology, a whole set of potential applications become

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Markus Schmidt · Alexander Kelle · Agomoni Ganguli-Mitra · Huib de Vriend Editors

Synthetic Biology The Technoscience and Its Societal Consequences

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Editors Dr. Markus Schmidt Organisation for Internationalen Dialog und Konfliktmanagement (IDC) Abt-Karl Gasse 19/21 1180 Wien Austria [email protected] Agomoni Ganguli-Mitra University of Zurich Institute of Biomedical Ethics Zollikerstr. 115 8008 Zurich Switzerland

Dr. Alexander Kelle University of Bath Department of European Studies and Modern Languages Claverton Down Bath United Kingdom Huib de Vriend De Vriesstraat 13 2613 CA Delft LIS Consult Netherlands

ISBN 978-90-481-2677-4 e-ISBN 978-90-481-2678-1 DOI 10.1007/978-90-481-2678-1 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2009927336 © Springer Science+Business Media B.V. 2009 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Contents

1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Markus Schmidt

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2 That Was the Synthetic Biology That Was . . . . . . . . . . . . . . . . . . . . . . . . . Luis Campos

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3 An Introduction to Synthetic Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Carolyn M.C. Lam, Miguel Godinho, and Vítor A.P. Martins dos Santos 4 Computational Design in Synthetic Biology . . . . . . . . . . . . . . . . . . . . . . . 49 Maria Suarez, Guillermo Rodrigo, Javier Carrera, and Alfonso Jaramillo 5 The Ethics of Synthetic Biology: Outlining the Agenda . . . . . . . . . . . . . 65 Anna Deplazes, Agomoni Ganguli-Mitra, and Nikola Biller-Andorno 6 Do I Understand What I Can Create? . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 Markus Schmidt 7 Security Issues Related to Synthetic Biology . . . . . . . . . . . . . . . . . . . . . . . 101 Alexander Kelle 8 The Intellectual Commons and Property in Synthetic Biology . . . . . . . 121 Kenneth A. Oye and Rachel Wellhausen 9 Governing Synthetic Biology: Processes and Outcomes . . . . . . . . . . . . . 141 Joyce Tait 10 Synthetic Biology and the Role of Civil Society Organizations . . . . . . . 155 Dirk Stemerding, Huib de Vriend, Bart Walhout, and Rinie van Est v

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Contents

11 Summary and Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 Alexander Kelle Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185

Contributors

Nikola Biller-Andorno Institute of Biomedical Ethics, University of Zurich, Switzerland, biller-andornu@et