Synthetic Materials: Processing and Surface Modifications for Vascular Tissue Engineering

Cardiovascular disease is a prominent issue in developed countries, notably the United States, and is expected to further escalate. As a result, the demand for “off the shelf” vascular grafts will concurrently increase. These readily available grafts for

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Beat H. Walpoth · Helga Bergmeister Gary L. Bowlin · Deling Kong · Joris I. Rotmans Peter Zilla  Editors

Tissue-Engineered Vascular Grafts

Reference Series in Biomedical Engineering Tissue Engineering and Regeneration Series Editor Heinz Redl Ludwig Boltzmann Institute for Experimental and Clinical Traumatology/AUVA Research Center Austrian Cluster for Tissue Regeneration Wien, Austria

This series Tissue Engineering and Regeneration consists of comprehensive reference texts encompassing the biological basis of tissue regeneration, basic principles of tissue engineering, and the current state-of-the-art in tissue engineering of specific tissues and organs. Each volume combines established fundamentals and the latest developments, thus forming an invaluable collection for both experienced researchers as well as practitioners from other areas of expertise. The spectrum of topics ranges from the use of cells for tissue regeneration and tissue engineering, growth factors and biological molecules affecting tissue development and regeneration, to the specific roles of biophysical factors in tissue development and regeneration. Tissue engineering lies at the crossroads of medicine, life sciences, and engineering. The field has developed extensively over the last two decades, addressing the requirements of tissue and organ replacement as well as regeneration in a variety of congenital, traumatic, disease, and aging-related conditions, including some of the most critical unmet challenges in modern medicine. Both our increased understanding of the biological basis of tissue engineering as well as significant technological advances mean that engineering design principles can now be used for the de novo construction of functional tissue replacements that meet the requirements of research and clinical applications. More information about this series at http://www.springer.com/series/13441

Beat H. Walpoth • Helga Bergmeister Gary L. Bowlin • Deling Kong Joris I. Rotmans • Peter Zilla Editors

Tissue-Engineered Vascular Grafts With 86 Figures and 21 Tables

Editors Beat H. Walpoth Emeritus, Cardiovascular Surgery and Research University Hospital and University of Geneva Geneva, Switzerland

Helga Bergmeister Center for Biomedical Research Medical University Vienna Vienna, Austria

Gary L. Bowlin Department of Biomedical Engineering University of Memphis Memphis, TN, USA

Deling Kong Key Laboratory of Bioactive Materials of the Ministry of Education College of Life Sciences, Nankai University Tianjin, China

Joris I. Rotmans Department of Internal Medicine Leiden University Medical Center Leiden, The Netherlands

Peter Zilla Chris Barnard Division of Cardiothoracic Surgery, Groote Schuur Hospital University of Cape Town Cape Town, South Africa

ISBN 978-3-030-05335-2 ISBN 978-3-030-05336-9 (eBook) ISBN 978-3-030-05337-6 (print and electronic bundle) https://doi.org/10.1007/978-3-030-05336-9 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or par

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