Systemic Lupus Erythematosus
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Glossary
Systematic Review Definition A Systematic Review is a scientific investigation of the literature that summarizes the best available evidence on a subject matter. Systematic reviews have a well-designed protocol that includes a focused research question, a specific search strategy, how studies will be identified and selected, inclusion and exclusion criteria, the types of data to be abstracted from each article, and how the data will be synthesized.
Systemic Lupus Erythematosus Definition SLE is an uncommon multi-system autoimmune rheumatological condition that is characterized by relapses and remissions. It is a world-wide disease that most commonly affects young women of child-bearing age. The cause of SLE is unclear but thought to involve a complex interplay of genetic and environmental factors. Diagnosis is based on clinical features and laboratory investigations. Treatment depends on severity of the disease and is mainly with immunosuppressive drugs and symptomatic medications.
Systemic Sclerosis Synonyms Scleroderma Definition Systemic Sclerosis is a chronic disease characterized by excessive deposits of collagen in the skin and other organs. Severe form of systemic sclerosis can be fatal as a result of heart, kidney, lung or bowel damage.
T-Test Definition Statistical test whether two means are different with a probability of 1-p.
Targeted Agents Definition Drugs that target different pathways that are responsible for the growth of tumor cells including proliferation and angiogenesis. Targeted Agents can target only one pathway or can block several pathways at the same time.
TB ▶ Tuberculosis
TCP ▶ Tumor Control Probability
TCS ▶ High Potency Topical Corticosteroids
TDO ▶ Tryptophan Degradation
Temozolomide Definition An oral imidazotetrazinone methylating agent that has demonstrated schedule-dependent activity in several cancers, including gliomas.
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